2013
DOI: 10.1111/jgs.12067
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High Blood Pressure and Cognitive Decline in Mild Cognitive Impairment

Abstract: Objectives To determine whether high blood pressure (BP) levels are associated with faster decline in specific cognitive domains. Design Prospective longitudinal cohort. Setting Uniform Data Set of the National Institutes of Health, National Institute on Aging Alzheimer's Disease Centers. Participants One thousand three hundred eighty-five participants with a diagnosis of mild cognitive impairment (MCI) and measured BP values at baseline and two annual follow-up visits. Measurements Neuropsychological … Show more

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Cited by 103 publications
(89 citation statements)
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“…The guidelines did not take into account cognitive and functional outcomes associated with hypertension. These outcomes are also important to consider because hypertension is a risk factor for mild cognitive impairment (MCI) and dementia, including Alzheimer's disease (3)(4)(5)(6)(7). Nearly 70% of persons in the United States who are 60 years or older have hypertension (8), and it is estimated that 13.8 million persons older than 65 years will develop Alzheimer's disease by 2050 (9).…”
mentioning
confidence: 99%
“…The guidelines did not take into account cognitive and functional outcomes associated with hypertension. These outcomes are also important to consider because hypertension is a risk factor for mild cognitive impairment (MCI) and dementia, including Alzheimer's disease (3)(4)(5)(6)(7). Nearly 70% of persons in the United States who are 60 years or older have hypertension (8), and it is estimated that 13.8 million persons older than 65 years will develop Alzheimer's disease by 2050 (9).…”
mentioning
confidence: 99%
“…Zdrowie -Rekreacja -Edukacja -Seniorzy czy schorzenia sercowo-naczyniowe, w tym udar mózgu, które same w sobie stanowią czynnik ryzyka deterioracji poznawczej (Lee et al, 2003;Cournot et al, 2006;Nelson et al, 2007;Sofi et al, 2007, Goldstein, 2013. Wskazuje się także na zjawiska wzrostu mózgowego przepływu krwi czy poprawy metabolizmu glukozy podczas wysiłku fizycznego.…”
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“…[22][23][24] A growing number of cohort studies show an association between hypertension and decreased cognitive functioning. [25][26][27][28] These studies have examined this association in a wide range of age groups including children, young adults, midlife adults, and older adults. For example, the Honolulu Asia Aging Study 29,30 found an association between untreated hypertension in midlife and the development of dementia in later life.…”
mentioning
confidence: 99%