The known The Australian HPV vaccination program has led to significant declines in a number of HPV-related conditions, including diagnoses of genital warts in young women and heterosexual men at sexual health clinics.The new We found marked declines in the proportions of young Indigenous women and men attending sexual health clinics for the first time who were diagnosed with genital warts following introduction of the HPV vaccination program, similar to declines among non-Indigenous young women and men.The implications Sustained high HPV vaccine coverage rates and monitoring are needed to close the gap between Indigenous and non-Indigenous Australians in the rates of cervical and other HPV-related cancers in older women.T he Australian national human papillomavirus (HPV) vaccination program commenced in April 2007. Free vaccination was provided to 12e13-year-old girls in schools; this was supplemented by a 3-year catch-up program for 13e18-year-old girls in schools and for 18e26-year-old women through family doctors in July 2007.1 In 2013, boys were added to the program, providing free HPV vaccination to 12e13-year-old boys in schools and, for 2 years, a catch-up program for 14e15-year-old boys. Australia uses the quadrivalent HPV vaccine (Gardasil), protecting against HPV types 6 and 11, which cause ano-genital warts, and HPV types 16 and 18, which cause cancer.
2,3The Australian HPV vaccination program has had very promising results. High coverage rates among vaccine-eligible girls have been achieved, 73% receiving all three doses in 2010. 4 Significant reductions in the prevalence of HPV-related conditions have been seen; diagnoses of genital warts in young women and heterosexual men at sexual health clinics, 5,6 inpatient treatment of genital warts at private hospitals, 7 hospital admissions for genital warts, 8 the prevalence in young women of HPV types targeted by the quadrivalent vaccine, 9,10 and the incidence of high grade cervical abnormalities 11 have all declined.Measuring the impact of the HPV vaccination program in Aboriginal and/or Torres Strait Islander (Indigenous) people is important because cervical cancer rates among Indigenous women are twice as high as among non-Indigenous women. 12 Similar findings have been reported overseas; a meta-analysis of data from 35 studies found that indigenous women had elevated risks of invasive cervical cancer and related mortality (pooled risk ratios, 1.72 and 3.45 respectively).13 Indigenous Australians experience poorer outcomes than non-Indigenous people for a range of conditions, 14 including some sexually transmissible infections (STIs). [15][16][17] In response to these inequities, the Australian Government initiated the Closing the Gap program in 2008, 18 followed in 2014 by the Fourth NationalAboriginal and Torres Strait Islander Blood-borne Viruses and STI Strategy, 2014e2017, which includes the aim of achieving high rates of HPV vaccination.
19Despite their disproportionately high rates of cervical cancer, there is a lack of information on HPV vacc...