High-Definition Chromocolonoscopy vs. High-Definition White Light Colonoscopy for Average-Risk Colorectal Cancer Screening

Kahi, Charles J.; Anderson, Joseph C.; Waxman, Irving; Kessler, William R.; Imperiale, Thomas F.; Li, Xiaochun; Rex, Douglas K.

doi:10.1038/ajg.2010.51

Cited by 192 publications

(148 citation statements)

References 22 publications

Supporting

Mentioning

133

Contrasting

Unclassified

Order By: Relevance

“…In other words, our practice will not be modified by this finding. Therefore, we fully agree with the authors in their conclusion that their results do not support the routine use of high-definition chromocolonoscopy for colorectal cancer screening in average-risk patients ( 10 ).…”

supporting

confidence: 79%

Editorial: An Advanced Chromocolonoscopic Picture Is Worth a Thousand Words, but Is It Worth the Effort?

Mönkemüller

Zimmermann

2010

American Journal of Gastroenterology

View full text Add to dashboard Cite

Chromocolonoscopy is a commonly used advanced or multimodal colon imaging method to interrogate the colon mucosa and colon polyps. The two main objectives of chromocolonosopy are to (a) detect a colon polyp and (b) defi ne (differentiate) the lesion. Although data supporting the use of chromocolonoscopy for colon polyp detection are not strongly founded, this technique may be helpful in differentiating colon polyps and may aid in their endoscopic resection.

show abstract

supporting

confidence: 79%

Editorial: An Advanced Chromocolonoscopic Picture Is Worth a Thousand Words, but Is It Worth the Effort?

Mönkemüller

Zimmermann

2010

American Journal of Gastroenterology

View full text Add to dashboard Cite

show abstract

“…Proportion of patient excluded varied from 4% 35 , 5% 36 , 8% 37 to 9% 15 . Intentto-treat analysis would have dictated an adjustment of the ADR reported in each of these studies by the proportion of patients excluded due to poor bowel preparation (see values in [ ] in Table 3).…”

Section: Discussionmentioning

confidence: 99%

“…Distal = distal to the splenic flexure. definition, wide-angle endoscope 15,[21][22][23][24][25] ; narrow band imaging [26][27][28] ; transparent hood attached to the tip of the colonoscope 26,29,30 withdrawal time >6 min 31,32 or modified (e.g. split-dose) bowel preparation 33,34 .…”

Section: Discussionmentioning

confidence: 99%

“…13 Despite these encouraging features chromoendoscopy for screening and surveillance has not been performed routinely by endoscopists in the United States (US). 10,[14][15][16] Because the water method is easy-to-use consideration for combining it with chromoendoscopy to increase ADR may have merit. The objective of this current retrospective nonrandomized review is to compare ADR in colonoscopy performed using the air method, water method alone, and water method with indigo carmine added.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

The water method combined with chromoendoscopy enhances adenoma detection

Leung¹,

Ransibrahmanakul²,

Toomsen³

et al. 2011

jig

View full text Add to dashboard Cite

Background:The water method is easy-to-learn and improves colonoscopy outcomes. Dye-spray chromoendoscopy enhances ADR but has not been widely accepted for routine application in screening or surveillance colonoscopy. Hypothesis: With dye added to the water used in the water method, ADR can be enhanced compared with the water or air method alone. Objective: To compare ADR determined by the air method, water method alone, and water method with indigo carmine (0.008%) added. Design: Review of prospectively collected data in a performance improvement program. Setting: VA endoscopy unit. Patient: Screening or surveillance colonoscopy. Methods: Patients (n=50/group) underwent colonoscopy with each of the three methods. Water method involved warm water infusion in lieu of air insufflation coupled with removal of residual air by suction and residual feces by water exchange. ADR and procedural data were collected prospectively to monitor performance. Main Outcome Measurements: ADR. Results: ADR in the air method, water method alone and water method with indigo carmine were 36%, 40% and 62%, respectively. Water method with indigo carmine produced significantly higher ADR than the air or water method alone (p<0.05). Limitations: Non-randomized data, single VA site, retrospective comparison. Absence of significant difference between air and water methods could be a type II error due to small number of patients Conclusions: The approach with indigo carmine added to the water used in the water method yielded significantly higher ADR than the water or the air method alone. The data suggest that a prospective RCT to compare the different methods is warranted.

show abstract

“…Indigo carmine is a most frequently used contrast dye, pooling in mucosal grooves and depressed areas without being absorbed by the mucosal glands, allowing better characterization of mucosal surface. Pancolonic chromoendoscopy increased the detection of flat and small adenomas when compared to standard endoscopy (SE) in almost all available studies, but because of its longer withdrawal time, long learning curve and costs its routine use appears not to be beneficial for average-risk colorectal cancer screening [27][28][29]. On the other hand, its routine use in patients at higher risk, with inflammatory bowel disease or known or suspected hereditary syndromes with accelerated carcinogenesis is recommended by European Society of Gastrointestinal Endoscopy (ESGE) [30].…”

Section: Introductionmentioning

confidence: 99%

Advances in endoscopic diagnosis of colorectal cancer

Čavlina¹,

Rustemović²

2017

Rad Hrvatske akademije znanosti i umjetnosti

View full text Add to dashboard Cite

SummaryColorectal cancer (CRC) is the third most commonly diagnosed malignant tumor and the fourth leading cause of cancer death in the world. Since it is known that most of colorectal cancers arise from adenomatous polyps, screening programmes were developed in order to improve detection of polyps and early diagnosis of carcinoma. Colonoscopy is the gold standard for diagnosis of CRC. Because of its high adenoma missing rates and lower ability to differentiate between benign and malignant lesions novel techniques are being developed in order to improve mucosal visualization, reduce adenoma missing rates and enable in-vivo optical diagnosis. Methods can roughly be divided into three categories, ones that present improved visualization techniques (endoscopes with increased field of view, auxiliary imaging devices, so called addon devices), ones that enable more detail tissue characterization presenting the possibility for virtual biopsy (conventional or virtual chromoendoscopy, confocal laser endomicroscopy and endocytoscopy), and other minimally or non-invasive techniques.Further investigation is needed, but hopefully these innovations with continuous technical improvement might help to reduce the colorectal cancer incidence and mortality.

show abstract

High-Definition Chromocolonoscopy vs. High-Definition White Light Colonoscopy for Average-Risk Colorectal Cancer Screening

Cited by 192 publications

References 22 publications

Editorial: An Advanced Chromocolonoscopic Picture Is Worth a Thousand Words, but Is It Worth the Effort?

Editorial: An Advanced Chromocolonoscopic Picture Is Worth a Thousand Words, but Is It Worth the Effort?

The water method combined with chromoendoscopy enhances adenoma detection

Advances in endoscopic diagnosis of colorectal cancer

Contact Info

Product

Resources

About