2020
DOI: 10.1016/j.gie.2019.12.052
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High-definition colonoscopy for improving adenoma detection: a systematic review and meta-analysis of randomized controlled studies

Abstract: Background and Aims: Previous meta-analysis showed marginal benefit of high-definition white-light endoscopy (HD-WLE) over standard-definition colonoscopy (SDC) for adenoma detection, but with residual uncertainty due to inclusion of nonrandomized studies. We aimed to further assess the effect of HD-WLE on adenoma detection by including only randomized controlled trials (RCTs). Methods: A literature search was performed for RCTs evaluating HD-WLE versus SDC in terms of adenoma, advanced adenoma, and serrated s… Show more

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Cited by 45 publications
(18 citation statements)
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References 33 publications
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“…Moreover, in this study, the ADR was 16.5 %, below that recommended by the American Society for Gastrointestinal Endoscopy, which considers the target ADR of 20 % to be a quality indicator [13]. The low ADR observed in this study may be explained by the characteristics of the population screened within this study, or by the lack of imaging magnification modes or high-resolution endoscopic devices used, which may have compromised our ability to diagnose small lesions [14][15][16][17][18].…”
Section: Discussioncontrasting
confidence: 56%
“…Moreover, in this study, the ADR was 16.5 %, below that recommended by the American Society for Gastrointestinal Endoscopy, which considers the target ADR of 20 % to be a quality indicator [13]. The low ADR observed in this study may be explained by the characteristics of the population screened within this study, or by the lack of imaging magnification modes or high-resolution endoscopic devices used, which may have compromised our ability to diagnose small lesions [14][15][16][17][18].…”
Section: Discussioncontrasting
confidence: 56%
“…A recent meta-analysis of randomized controlled trials confirms a definite, but modest, impact on adenoma, serrated polyp, and advanced adenoma detection rates with the use of high-definition colonoscopes. 35 Although high-definition imaging is now a standard feature of newergeneration endoscopes, many legacy lower-definition instruments still remain in circulation. Available evidence suggests that upgrading older equipment to high-definition colonoscopes is likely an effective strategy for endoscopy units to improve the quality of screening and surveillance colonoscopy.…”
mentioning
confidence: 99%
“…190 The use of high definition scopes over standard definition has been shown to help in adenoma detection and is now being preferred at many facilities. 191 Chromoendoscopy (use of dyes) in increasing detection of polyps has been studied the screening population with some benefit. 192 Most studies, however, compared chromoendoscopy with standard definition scopes and not high definition colonoscopy, which is currently the standard for use in screening colonoscopy.…”
Section: Quality Measures For Colonoscopymentioning
confidence: 99%