High-definition Optical Coherence Tomography Findings in Acute Idiopathic Blind Spot Enlargement (AIBSE) Syndrome

Piri, Niloofar; Kaplan, Henry J.; Sigford, Douglas Kenneth; Tezel, Tongalp H.

doi:10.3109/09273948.2013.872802

Cited by 12 publications

(32 citation statements)

References 6 publications

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“…In these conditions, known collectively as the White Dot Syndromes or AZOOR complex disorders, visible fundus findings are often subtle or absent 3 4 5 . However, optical coherence tomography has shown morphological changes in the retinal layer containing photoreceptor outer segments 6 7 8 9 10 .…”

mentioning

confidence: 99%

Spontaneous Regeneration of Human Photoreceptor Outer Segments

Horton

Parker

Botelho

et al. 2015

Sci Rep

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Photoreceptors are damaged in many common eye diseases, such as macular degeneration, retinal detachment, and retinitis pigmentosa. The development of methods to promote the repair or replacement of affected photoreceptors is a major goal of vision research. In this context, it would be useful to know whether photoreceptors are capable of undergoing some degree of spontaneous regeneration after injury. We report a subject who lost retinal function in a wide zone around the optic disc, giving rise to massive enlargement of the physiological blind spot. Imaging with an adaptive optics scanning laser ophthalmoscope (AOSLO) showed depletion of cone outer segments in the affected retina. A year later visual function had improved, with shrinkage of the enlarged blind spot. AOSLO imaging showed repopulation of cone outer segments, although their density remained below normal. There was a one-to-one match between sites of formerly missing outer segments and new outer segments that had appeared over the course of the year’s recovery. This correspondence provided direct morphological evidence that damaged cones are capable, under some circumstances, of generating new outer segments.

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confidence: 99%

Spontaneous Regeneration of Human Photoreceptor Outer Segments

Horton

Parker

Botelho

et al. 2015

Sci Rep

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“…20 OCT may show a loss or irregularity of the ellipsoid layer in corresponding area of visual field defect. 26 An enlarged blind spot can only be the sole detected finding, which may resemble to temporal field defect, and mis-interpret if not respect to the midline but our patient had bilateral left hemianopic field with normal macular scan.…”

Section: Discussionmentioning

confidence: 62%

Transient visual field loss after COVID-19 vaccination: Experienced by ophthalmologist, case report

Jumroendararasame

Panyakorn

Othong

et al. 2021

American Journal of Ophthalmology Case Reports

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Purpose The first reported case of bilateral transient visual field defect, experienced by an ophthalmologist, which developed shortly after COVID-19 vaccination (CoronaVac, Sinovac Biotech Ltd., Beijing, China) and confirmed by computerized automated perimetry. Observation The patient is a 42-year-old Thai ophthalmologist. He developed blurred vision within an hour after the second dose of COVID-19 vaccination. We described his self-observed of sequential symptoms, chronologic events, and management steps. The visual field of left congruous hemianopia with respect to vertical midline was detected with computerized automated perimetry. The possible mechanism could be related to an acute vasospasm of the artery in the postchiasmatic visual pathway, triggered by COVID-19 vaccine, Corona Vac. Conclusion and importance With increasing use of the COVID-19 vaccine in the near future, it would be prudent for medical staff and ophthalmologists to be considered and aware of this associated condition.

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“…Optical coherence tomography (OCT) displays defects in the IS/OS junction and the cone outer segment tip (COST) line involving the peripapillary region extending towards the macula. 4 , 5 , 6 Finally, multifocal electroretinography (mf-ERG) may be employed and shows attenuated responses around the area of the normal blind spot. 1 , 2 , 5 …”

Section: Introductionmentioning

confidence: 99%

“… 4 , 5 , 6 Finally, multifocal electroretinography (mf-ERG) may be employed and shows attenuated responses around the area of the normal blind spot. 1 , 2 , 5 …”

Section: Introductionmentioning

confidence: 99%