High-density cervical ureaplasma urealyticum colonization in pregnant women

Ranđelović, Gordana; Kocić, Branislava; Miljković-Selimović, Biljana; Mladenović-Antić, Snežana; Stojanović, Predrag; Stefanović, Milan

doi:10.2298/vsp0608737r

Cited by 5 publications

(4 citation statements)

References 26 publications

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“…Interestingly, there was also an association between HPV and U. urealyticum , but only in patients with a high colonization rate [18]. Further, high-density cervical U. urealyticum colonization may be a risk factor for premature rupture of membranes, chorioamnionitis and preterm delivery [19, 20].…”

Section: Discussionmentioning

confidence: 99%

An epidemiological survey of Mycoplasma hominis and Ureaplasma urealyticum in gynaecological outpatients, Rome, Italy

et al. 2013

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The objective of this study was to assess the prevalence of Ureaplasma urealyticum and Mycoplasma hominis infections and to investigate associations between their presence in the lower female genital tract and lifestyle characteristics. The study was performed on a population of 3115 women, comparing the demographic and behavioural characteristics of 872 women with U. urealyticum infection and 142 women with M. hominis with uninfected women, using univariate and multiple logistic regression analysis. The prevalence of infection with U. urealyticum was 28% and M. hominis was 4.6%. In multivariate logistic regression analysis, intrauterine device, number of sexual partners and age (<35 years) were significantly associated with U. urealyticum while previous induced abortion, condom use and young age at first intercourse (<16 years) were associated with M. hominis infection. U. urealyticum infection presents the same demographic and behavioural characteristics of a sexually transmitted disease. The unprotective role of condom use suggests a non-sexual mode of transmission of M. hominis infection.

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Section: Discussionmentioning

confidence: 99%

An epidemiological survey of Mycoplasma hominis and Ureaplasma urealyticum in gynaecological outpatients, Rome, Italy

et al. 2013

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“…A previous research conducted in Belgrade reported the prevalence of Chlamydia trachomatis genital infection of 30.3% among sexually active female adolescents aged 19 years, who visited the National Institute for Mother and Child Health (9). Other studies were aimed at specific groups, such as women with premature delivery (10) or microorganisms closely related to Chlamydia trachomatis such as Ureaplasma (11). In general, the results mentioned above, as well as other similar studies, could suffer from selection bias since their methods were not based on epidemiological backgrounds.…”

Section: Introductionmentioning

confidence: 99%

Monitoring of Chlamydia Trachomatis Genitourinary Infection in Women - Analytical Comparative Study Using Public Health Records from Two Balkan Countries

Arsić

Мilоvаnоvić

Ferati

et al. 2016

Cent Eur J Public Health

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SUMMARYAim: This study investigated the cumulative incidence of Chlamydia trachomatis infection in women treated in gynaecology departments of healthcare facilities in two towns in Serbia and one town in the Former Yugoslav Republic (FYR) of Macedonia, including their medical records in public health reports.Methods: A cross-sectional observational research design with retrospective data collection during a five-year period (2008-2012) originated from women treated as in-and out-patients. The data included the results of cervical and urethral swab testing on Chlamydia trachomatis infection and women's gynaecological diagnoses in Pomoravlje County (the Institute of Public Health Cuprija "Pomoravlje" in Cuprija, Alba outpatient clinic, Paracin) and in Skopje (Clinic for Obstetrics and Gynaecology, "Mikrolab" laboratory).Results: The incidence of positive ELISA assay from samples from the Institute of Public Health "Pomoravlje" Cuprija and polyclinic Alba was 6.5% and 12.5%, respectively (p < 0.01). The incidence of positive DFA test from samples from the Clinic for Obstetrics and Gynaecology, Skopje and "Mikrolab" laboratory was 18.8% and 15.2%, respectively (p = 0.20). In Pomoravlje County and in Skopje 7.5% and 17.6% of urethral swab samples were positive for Chlamydia trachomatis, respectively (p < 0.01). The rate of microbiological samples tested for Chlamydia trachomatis in Pomoravlje County and Skopje was 48.4% and 21.2%, respectively (p < 0.01). One-year incidences of Infectio sexuales chlamydiales (A56) from 2007-2011 were significantly different among three data settings relating to Serbia, the FYR of Macedonia and Pomoravlje County (p < 0.001).Conclusions: The incidence of Chlamydia trachomatis positive cervical and urethral swabs in our study were highly variable between countries and within individual hospitals and caused by many factors.

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“…Существует также мнение, что определяющую роль в патогенезе неблагоприятного воздействия генитальных микоплазм на мать, плод и новорожденного играет не столько сам факт обнаружения данных микроорганизмов в половых путях матери, сколько степень их колонизации, т.е. чем выше концентрация гениталь-ных микоплазм, тем чаще наблюдаются преждевременное излитие околоплодных вод, преждевременные роды, рождение детей с низкой массой тела, послеродовый эндометрит, увеличивается частота вертикальной передачи инфекции [15,16]. Участие урогенитальных микоплазм в развитии большого числа патологических состояний в гинекологии и акушерстве диктует необходимость своевременной диагностики и, при необходимости, этиопатогенетической терапии [5].…”

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Influence of the Massiveness of Infection of the Genital Tract With Urogenital Mycoplasmas on the Course and Outcomes of Pregnancy in Women of the Amur Region

Vlasova¹,

Suprun²,

Suprun³

et al. 2018

Bulletin Physiology and Pathology of Respiration

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In order to study the role of urogenital mycoplasmas on the course and outcomes of pregnancy, depending on its quantitative assessment using the real-time PCR, 159 rural women of the Amur region were examined. Infection with Ureaplasma species (spp.) was revealed in 51.2% of cases, among them in clinically significant concentrations (in the form of monoinfection or in combination with other opportunistic microorganisms) it was found in 39.0% of cases. Mycoplasma hominis in clinically significant concentration was determined in 15.1% of pregnant women, among them in 8.8% it was in combination with Ureaplasma spp. The effects of massive infection of the genital tract with urogenital mycoplasmas on the course and outcomes of pregnancy were evaluated in 85 patients. Four groups of pregnant women were formed according to the results of clinical and laboratory examinations. Group 1 (n=19) included pregnant women with convenional normocenosis (Lactobaccilus spp. ≥106 GE/mL, Ureaplasma spp ≥104 GE/mL); group 2 (n=23) included patients with identified urogenital mycoplasma (Ureaplasma spp and Mycoplasma hominis) in clinically significant concentrations in combination with other opportunistic microorganisms (Streptococcus agalactiae, Enterobacteriaceae, Staphylococcus spp., Gardnerella vaginalis, Bacteroides spp. and others). Pregnant women with vaginal dysbiosis (Lactobacillus sp. ≤106 GE/mL) and the absence of urogenital mycoplasmas were included in group 3 (n=13). The control group included 30 pregnant women with normal vaginal flora and the absence of urogenital mycoplasmas. The exclusion criteria were the identification of unconditional pathogens (Chlamydia trachomatis, Neisseria gonorrhoeae, Trichomonas vaginalis, Mycoplasma genitalium) and the activation of herpesvirus infections (HSV and CMV). As a result of the study, pregnant women in the main groups were 4.7-7 times more often to be diagnosed with fetal growth retardation syndrome; 2.0–3.2 times more often to have placental insufficiency compared with subjects in the control group. Premature birth in women of group 1 was registered 3.3 times more often than in the control group. In the same group, there was a tendency to increase the number of pregnant women with a long anhydrous period and premature discharge of amniotic fluid.

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High-density cervical ureaplasma urealyticum colonization in pregnant women

Abstract: Cervical colonization with U. urealyticum > or = 10(4) is more frequent in pregnant women with risk pregnancy than in pregnant women with normal term delivery. High-density cervical U. urealyticum colonization should be observed as a possible etiological factor for PROM.

Cited by 5 publications

References 26 publications

An epidemiological survey of Mycoplasma hominis and Ureaplasma urealyticum in gynaecological outpatients, Rome, Italy

An epidemiological survey of Mycoplasma hominis and Ureaplasma urealyticum in gynaecological outpatients, Rome, Italy

Monitoring of Chlamydia Trachomatis Genitourinary Infection in Women - Analytical Comparative Study Using Public Health Records from Two Balkan Countries

Influence of the Massiveness of Infection of the Genital Tract With Urogenital Mycoplasmas on the Course and Outcomes of Pregnancy in Women of the Amur Region

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