High-dose intravenous immunoglobulin therapy for novel coronavirus disease 2019: a brief report of two cases

What's new in critical illness and injury science? Intravenous immunoglobulin for COVID-19 with severe or critical illness

“…[ 3 ] After multiple case reports and series touted its efficacy, many began to use IVIG in the treatment of severe and critically ill COVID-19 patients, particularly for patients with central nervous system manifestations. [ 10 11 12 13 14 15 16 17 18 ] Of note, many of these cases had comorbid illnesses or chronically immunosuppressed states, for which IVIG may be an appropriate treatment,[ 10 11 18 19 ] while others have touted high-dose IVIG pulse therapy as a means to prevent chronically immunosuppressed patients from contracting COVID-19. [ 20 ]…”