High Dose Rate Treatment of a Maxillary Sarcomatoid Carcinoma: A Case Report

Asbury, Lynn; Candelaria, Sandra; Rudak, Faye; Stutzman, Charles D.; Lake, David E.

doi:10.1016/0958-3947(92)90029-f

Cited by 4 publications

(2 citation statements)

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“…Tables I through IV summarize the collective published experience with maxillary and sphenoid benign and malignant tumors according to histopathology and incidence. 7–50 , 51–100 , 101–150 , 151–200 , 201–250 , 251–300 , 301–350 , 351–400 , 401–450 , …”

Section: Resultsmentioning

confidence: 99%

Factors in the Pathogenesis of Tumors of the Sphenoid and Maxillary Sinuses: A Comparative Study

Reino

2000

The Laryngoscope

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Objectives/Hypothesis To explain the processes that lead to the development of tumors in the maxillary and sphenoid sinuses. Study Design A 32‐year review of the world's literature on neoplasms of these two sinuses and a randomized case‐controlled study comparing the normal mucosal architecture of the maxillary to the sphenoid sinus. Methods Analysis of a 32‐year world literature review reporting series of cases of maxillary and sphenoid sinus tumors. Tumors were classified by histological type and separated into subgroups if an individual incidence rate was reported. Histomorphometry of normal maxillary and sphenoid sinus mucosa was performed in 14 randomly selected patients (10 sphenoid and 4 maxillary specimens). Specimens were fixed in 10% formalin, embedded in paraffin, and stained with periodic acid–Schiff (PAS) and hematoxylin. Histomorphometric analysis was performed with a Zeiss Axioscope light microscope (Carl Zeiss Inc., Thornwood, NY) mounted with a Hamamatsu (Hamamatsu Photonics, Tokyo, Japan) color‐chilled 3 charge coupled device digital camera. The images were captured on a 17‐inch Sony (Sony Corp., Tokyo, Japan) multiscan monitor and analyzed with a Samba 4000 Image Analysis Program (Samba Corp., Los Angeles, CA). Five random areas were selected from strips of epithelium removed from each sinus, and goblet and basal cell measurements were made at magnifications ×100 and ×400. Results The literature review revealed that the number and variety of tumors in the maxillary sinus are much greater than those in the sphenoid. The incidence of metastatic lesions to each sinus is approximately equal. No recognized pattern of spread from any particular organ system could be determined. On histomorphometric study there were no statistically significant differences between the sinuses in the concentration of goblet cells, basal cells, or seromucinous glands. Conclusions Factors involved in the pathogenesis of tumors of the maxillary and sphenoid sinuses include differences in nasal physiology, embryology, morphology, and topography. There are no significant histological differences in the epithelium and submucous glands between the two sinuses to explain the dissimilar formation of neoplasms.

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Section: Resultsmentioning

confidence: 99%

Factors in the Pathogenesis of Tumors of the Sphenoid and Maxillary Sinuses: A Comparative Study

Reino

2000

The Laryngoscope

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“…They are most frequently observed in the larynx, while the regions where they are less localized are the hypopharynx, oropharynx, sinuses and the nasal cavity (1). As indicated in the table prepared by Kumar, et al [4], the number of such cases is low [1,[5][6][7][8][9][10][11]. Only seven cases with maxillary localization have been reported in literature [10].…”

Section: Discussionmentioning

confidence: 99%

Spindle cell carcinoma (sarcomatoid carcinoma) of maxillary sinus and nasal cavity with orbital involvement: A rare case report and brief review of literature

Altınay¹,

Altinok²,

Namal³

et al. 2018

Dent Oral Craniofac Res

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Sarcomatoid (spindle cell) carcinoma is a unique variant of squamous cell carcinoma. So far very rare cases of sarcomatoid carcinoma with maxillary origin have been reported in the Pubmed based research. A new case of spindle cell squamous cell carcinoma with ptosis is reporting in a 65-year old Turkish man. The mass lesion was mainly localized in the maxillary sinus, nasal cavity and extending towards the orbital wall. The cells had a large vesicular nucleus and marked macronucleoles. Tumor cells showed strong immunreactivity comprising both sarcomatous and epithelial components. Case was reported as sarcomatoid carcinoma of maxilla based on these characteristics. The patient was at stage 4b in clinical staging and was regarded as non-operable. Intensity modulated radiotherapy technique was used and a regression at a rate of 1/3 was observed in the tumor.

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Sinonasal spindle cell carcinoma presenting with bilateral visual loss: A case report and review of the literature

2016

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Spindle cell carcinoma (SpCC) is a rare variant of squamous cell carcinoma (SCC). SpCC of sinonasal origin is relatively rare and more aggressive than normal SCC. It most commonly involves the maxillary sinus, and rarely the sphenoid sinus. The present study reports a case of sphenoid sinus SpCC presenting with bilateral visual loss. Following endoscopic sinus decompression surgery, the patient was referred to the Oncology Department for a staging workup, and subsequently received concurrent chemoradiotherapy; however, the vision of the patient was not recovered, despite treatment. To the best of our knowledge, this is the first reported case of synchronous inverted papilloma of the sphenoid sinus and SpCC presenting with optic nerve compression.

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High Dose Rate Treatment of a Maxillary Sarcomatoid Carcinoma: A Case Report

Cited by 4 publications

References 0 publications

Factors in the Pathogenesis of Tumors of the Sphenoid and Maxillary Sinuses: A Comparative Study

Factors in the Pathogenesis of Tumors of the Sphenoid and Maxillary Sinuses: A Comparative Study

Spindle cell carcinoma (sarcomatoid carcinoma) of maxillary sinus and nasal cavity with orbital involvement: A rare case report and brief review of literature

Sinonasal spindle cell carcinoma presenting with bilateral visual loss: A case report and review of the literature

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