2022
DOI: 10.4103/ijmr.ijmr_1062_20
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High expression of ZEB1 is associated with EMAST & metastasis in colorectal cancer patients

Abstract: Background & objectives: Transforming growth factor-beta (TGF-β) signalling pathway has been reported to be involved in metastasis and at the same time has been considered compellingly an important mediator of epithelial-to-mesenchymal transition (EMT). Besides, EMT process is maintained by zinc-finger E-box-binding homeobox 1 ( ZEB1 ) gene which is induced by TGF-β pathway. TGF-β has been shown to be associated with elevated microsatellite alterations at selected tetran… Show more

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