High-Flow Oxygen Therapy in Tracheostomized Subjects With Prolonged Mechanical Ventilation: A Randomized Crossover Physiologic Study

The effect of high-flow oxygen via tracheostomy on respiratory pattern and diaphragmatic function in patients with prolonged mechanical ventilation: A randomized, physiological, crossover study

“…Although a reduction in respiratory frequency has been reported, mainly during HFOT through the nasal route, [3] , [25] , [26] the results of studies using HFOT through a tracheostomy tube are varied. In contrast with our findings, Stripoli et al [9] and Lersritwimanmaen et al [28] did not report a significant difference in respiratory frequency during HFOT compared to conventional oxygen via T-piece in tracheostomized patients. In accordance with our results, Natalini et al [10] reported that HFOT led to a slight reduction in respiratory frequency in tracheostomized patients, mainly in those with higher respiratory frequency during standard oxygen.…”

“…In accordance with our results, Natalini et al [10] reported that HFOT led to a slight reduction in respiratory frequency in tracheostomized patients, mainly in those with higher respiratory frequency during standard oxygen. All these studies [9] , [10] , [28] applied HFOT at 50 L/min, while our patients received HFOT at 60 L/min. Multifactorial etiology, including methodological issues and an underlying complex patient pathophysiology, might have contributed to the different findings.…”

High-Flow Tracheal Oxygen for Tracheostomy Tube Removal in Lung Transplant Recipients

“…Of note, HFTO was well tolerated by all the patients. In line with our results, a recent study suggested that heat and humidification of inspired gas may improve comfort and tolerability and alleviate inspiratory effort compared to COT in tracheostomized patients [25]. Moreover, the incidence of barotrauma was negligible, which is especially relevant in LT recipients who are at increased risk for anastomotic leakage [26].…”

Terapia de alto flujo en pacientes con traqueostomía. Una revisión narrativa.

“…En otro estudio, 33 se comparó la terapia AF-TQT versus la utilización de tubo en T versus la ventilación con presión de soporte arrojando resultados similares en términos del producto presión-tiempo esofágico (PTPtot/br [cmH 2 O x s] y PTPtot/min [cmH 2 O x seg/min]). La PTPes por minuto fue significativamente mayor con AF-TQT y tubo en T, en comparación con PSV (153,5 ± 97,9, 163,5 ± 111,3 y 86,8 ± 51,1 cm H 2 O × s/min, respectivamente, p = 0,001), pero no fue diferente entre AF-TQT y O 2 convencional (p = 0,72).…”