High-frequency oscillatory response to illusory contour in typically developing boys and boys with autism spectrum disorders

Stroganova, Tatiana A.; Orekhova, Elena V.; Prokofyev, Andrey O.; Tsetlin, Marina M.; Gratchev, Vitaliy V.; Morozov, Alexei A.; Obukhov, Yu. V.

doi:10.1016/j.cortex.2011.02.016

Cited by 68 publications

(60 citation statements)

References 92 publications

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“…However, this is limited to perception and evidence showing unimpaired grouping in autism (Falter et al, 2010) shows that the local bias does not straightforwardly result in impaired perception of similarity relations. This is evident in the findings that ERP indices of grouping on the Kanizsa triangle or Mooney face tasks (Brown et al, 2005;Stroganova et al, 2012;Sun et al, 2012) are consistent with an enhanced participation of low-level processes in autism despite typical or quasi-typical behavioral performance. Moreover, in Falter et al's (2010) study of grouping by similarity versus grouping by proximity, some incidental issues concerning the extraction of low-level physical dimensions (here, color analysis) may be responsible for the diminished performance on similarity grouping.…”

Section: Reduced Generalizationsupporting

confidence: 56%

Veridical mapping in the development of exceptional autistic abilities

Mottron¹,

Bouvet²,

Bonnel³

et al. 2013

Neuroscience & Biobehavioral Reviews

210

162

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Superior perception, peaks of ability, and savant skills are often observed in the autistic phenotype. The enhanced perceptual functioning model (Mottron et al., 2006a) emphasizes the increased role and autonomy of perceptual information processing in autistic cognition. Autistic abilities also involve enhanced pattern detection, which may develop through veridical mapping across isomorphic perceptual and non-perceptual structures (Mottron et al., 2009). In this paper, we elaborate veridical mapping as a specific mechanism which can explain the higher incidence of savant abilities, as well as other related phenomena, in autism. We contend that savant abilities such as hyperlexia, but also absolute pitch and synaesthesia, involve similar neurocognitive components, share the same structure and developmental course, and represent related ways by which the perceptual brain deals with objective structures under different conditions. Plausibly, these apparently different phenomena develop through a veridical mapping mechanism whereby perceptual information is coupled with homological data drawn from within or across isomorphic structures. The atypical neural connectivity characteristic of autism is consistent with a developmental predisposition to veridical mapping and the resulting high prevalence of savant abilities, absolute pitch, and synaesthesia in autism.

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Section: Reduced Generalizationsupporting

confidence: 56%

Veridical mapping in the development of exceptional autistic abilities

Mottron¹,

Bouvet²,

Bonnel³

et al. 2013

Neuroscience & Biobehavioral Reviews

210

162

View full text Add to dashboard Cite

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“…The current data clearly suggest that the main deficit in ASD is in the 60 -120 Hz frequency band. Finally, we found only limited evidence for increased high-frequency activity in the ASD group as previously reported (Brown et al, 2005;Isler et al, 2010;Stroganova et al, 2012) as elevated gamma-band activity was limited to an upregulation of 25-60 Hz activity over frontocentral sensors.…”

Section: Discussionmentioning

confidence: 52%

“…In the auditory domain, reduced entrainment to auditory stimulation at 40 Hz in participants with ASD (Wilson et al, 2007) as well as their firstdegree relatives (Rojas et al, 2011) has been demonstrated. In contrast, during visual perception there is evidence for both hyperactivity and hypoactivity of gamma-band oscillations (Grice et al, 2001;Brown et al, 2005;Milne et al, 2009;Isler et al, 2010;Stroganova et al, 2012), raising the question of the link between high-frequency oscillations and perceptual dysfunctions in the disorder.…”

Section: Introductionmentioning

confidence: 83%

Impaired Gamma-Band Activity during Perceptual Organization in Adults with Autism Spectrum Disorders: Evidence for Dysfunctional Network Activity in Frontal-Posterior Cortices

Sun

Grützner²,

Bölte³

et al. 2012

Journal of Neuroscience

139

134

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Current theories of the pathophysiology of autism spectrum disorders (ASD) have focused on abnormal temporal coordination of neural activity in cortical circuits as a core impairment of the disorder. In the current study, we examined the possibility that gamma-band activity may be crucially involved in aberrant brain functioning in ASD. Magneto-encephalographic (MEG) data were recorded from 13 adult human participants with ASD and 16 controls during the presentation of Mooney faces. MEG data were analyzed in the 25-150 Hz frequency range and a beamforming approach was used to identify the sources of spectral power. Participants with ASD showed elevated reaction times and reduced detection rates during the perception of upright Mooney faces, while responses to inverted stimuli were in the normal range. Impaired perceptual organization in the ASD group was accompanied by a reduction in both the amplitude and phase locking of gamma-band activity. A beamforming approach identified distinct networks during perceptual organization in controls and participants with ASD. In controls, perceptual organization of Mooney faces involved increased 60 -120 Hz activity in a frontoparietal network, while in the ASD group stronger activation was found in visual regions. These findings highlight the contribution of impaired gamma-band activity toward complex visual processing in ASD, suggesting atypical modulation of high-frequency power in frontoposterior networks.

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“…Three studies, one of which included a repetitive transcranial magnetic stimulation (rTMS) component, have investigated gamma-band activity during the perception of Kanizsa figures in autism [54-56]. While these three EEG studies utilized Kanizsa figures, the stimuli and tasks differed.…”

Section: Gamma-band Responses To Visual Stimuli In Autismmentioning

confidence: 99%

“…Participants pressed buttons only for target stimuli. The third study, Stroganova et al [56], 23 children with autism and 23 typically developing children passively viewed Kanizsa squares and non-Kanizsa squares.…”

Section: Gamma-band Responses To Visual Stimuli In Autismmentioning

confidence: 99%

γ-Band Abnormalities as Markers of Autism Spectrum Disorders

2014

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Summary Autism is a behaviorally diagnosed neurodevelopmental disorder with no current biomarkers with high specificity and sensitivity. Gamma-band abnormalities have been reported in many studies of autism spectrum disorders. Gamma-band activity is associated with perceptual and cognitive functions that are compromised in autism. Some gamma-band deficits have also been seen in unaffected first-degree relatives, suggesting heritability of these findings. This review covers the published literature on gamma abnormalities in autism, the proposed mechanisms underlying the deficits, and the potential for translation into new treatments. Although the utility of gamma-band metrics as diagnostic biomarkers is currently limited, such changes in autism are also useful as endophenotypes, for evaluating potential neural mechanisms, and for use as surrogate markers of treatment response to interventions.

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High-frequency oscillatory response to illusory contour in typically developing boys and boys with autism spectrum disorders

Cited by 68 publications

References 92 publications

Veridical mapping in the development of exceptional autistic abilities

Veridical mapping in the development of exceptional autistic abilities

Impaired Gamma-Band Activity during Perceptual Organization in Adults with Autism Spectrum Disorders: Evidence for Dysfunctional Network Activity in Frontal-Posterior Cortices

γ-Band Abnormalities as Markers of Autism Spectrum Disorders

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