High-grade myxofibrosarcoma of the abdominal wall

Antbring, Richard; Parker, S.; Lordan, Jeffrey T; Windsor, Alastair

doi:10.1136/bcr-2017-219643

Cited by 3 publications

(6 citation statements)

References 39 publications

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“…Its presence on the abdominal wall is quite uncommon. It was only mentioned once in the English literature [6] .…”

Section: Clinical Discussionmentioning

confidence: 99%

“…Needle biopsy of the tumor is a considerable option [6] . We preferred not to perform it in our case to avoid the dissemination of tumor cells.…”

Section: Clinical Discussionmentioning

confidence: 99%

“…Overall survival for patients having localized MFS varies from 61 to 77 % at 5-year [19] . Knowing that MFS has a propensity for local recurrence (16 to 57 %), adjuvant radiotherapy has emerged as an efficient treatment for improving local control [6] .…”

Section: Clinical Discussionmentioning

confidence: 99%

“…Their occurrence in the abdominal wall is extremely rare. To our knowledge, It was described only once in the English literature [6] .…”

Section: Introduction and Importancementioning

confidence: 99%

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Myxofibrosarcoma of the abdominal wall : A case report and literature review

Beji

Bouassida

Chtourou

et al. 2022

International Journal of Surgery Case Reports

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“…Its presence on the abdominal wall is quite uncommon. It was only mentioned once in the English literature [6] .…”

Section: Clinical Discussionmentioning

confidence: 99%

“…Needle biopsy of the tumor is a considerable option [6] . We preferred not to perform it in our case to avoid the dissemination of tumor cells.…”

Section: Clinical Discussionmentioning

confidence: 99%

Section: Clinical Discussionmentioning

confidence: 99%

“…Their occurrence in the abdominal wall is extremely rare. To our knowledge, It was described only once in the English literature [6] .…”

Section: Introduction and Importancementioning

confidence: 99%

See 2 more Smart Citations

Myxofibrosarcoma of the abdominal wall : A case report and literature review

Beji

Bouassida

Chtourou

et al. 2022

International Journal of Surgery Case Reports

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“…About 77% of MFS cases occur in the extremities with a predilection for the upper extremities. Other areas of the body including the trunk (12%), retroperitoneum or mediastinum (8%) [4,6], abdominal wall [7], heart [8] have also been reported. As a soft tissue tumor that mainly occurs in the subcutaneous tissue, MFS of the head and neck is quite rare.…”

Section: Introductionmentioning

confidence: 99%

Myxofibrosarcoma of the mandible: a case report and review of the literature

Liu

Zhang

et al. 2020

BMC Oral Health

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Background: Myxofibrosarcoma (MFS) is a soft tissue sarcoma that commonly occurs in late adult life. It is mainly located in the subcutaneous soft tissues of extremities characterized by a high recurrence rate at the original site. MFS of the head and neck is rare, while it occurs in the maxilla and mandible is extremely rare. Case presentation: We report a case of MFS of the mandible in a 51-year-old female who presented with a painless gingival swelling and mobile, super-erupted right mandibular second and third molars. Panoramic x-ray and maxillofacial CT revealed an ill-defined radiolucent lesion surrounding the mandibular molars giving a teethfloating-in-air appearance. Histopathological examination showed scattered spindle and stellate cells with mild atypia distributed in the myxoid stroma. Only a few mitotic figures were identified and no area of tissue necrosis was found. The characteristic thin-walled and curvilinear vasculature were prominent. Immunohistochemistry analysis revealed the tumor cells being positive for vimentin and vascular CD31. CK, S-100, P63, HHF-35 stains were negative. The labeling index of Ki-67 was about 30%. Based on the histopathological and immunohistochemical examinations, the diagnosis of a low-grade MFS was established. This patient underwent a radical segmental excision with a 2-cm margin, supraomohyoid neck dissection and immediate reconstruction of the mandibular continuity defect with a fibular osteocutaneous free flap. This patient has been followed for 20 months to date and has remained disease free. Conclusions: This report describes a rare case of MFS of the mandible. Recognizing the histopathological features of MFS and applying the appropriate immunohistochemical examinations are crucial in establishing the correct diagnosis. Our case may provide diagnosis and treatment experiences of MFS occurs in the mandible.

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Giant myxofibrosarcoma of the esophagus treated by endoscopic submucosal dissection: A case report

Wang¹,

Zhao²,

Wang³

et al. 2023

World J Clin Cases

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BACKGROUND Myxofibrosarcoma (MFS) is a fibroblast-derived sarcoma that mainly occurs in subcutaneous tissue. MFS rarely occurs in the gastrointestinal tract, especially in the esophagus. CASE SUMMARY A 79-year-old male patient was admitted to our hospital for dysphagia for a week. Computed tomography and electronic gastroscopy showed that a giant mass was located 30 cm from the incisor and extended to the cardia. There was incomplete esophageal stenosis. Endoscopic pathology showed spindle cell lesions, which were considered inflammatory myofibroblast like hyperplasia. Considering the strong demands of the patient and his family, and the fact that most inflammatory myofibroblast tumors are benign, we decided to perform endoscopic submucosal dissection (ESD) even if the tumor size was giant (9.0 cm × 3.0 cm). Postoperative pathological examination resulted in a final diagnosis of MFS. MFS rarely occurs in the gastrointestinal tract, especially in the esophagus. Surgical resection and local adjuvant radiotherapy are the first choices to improve the prognosis. This case report firstly described the ESD for esophageal giant MFS. It suggests that ESD may be an alternative treatment for primary esophageal MFS. CONCLUSION This case report for the first time describe the successful treatment of a giant esophageal MFS by ESD, suggesting that ESD may be an alternative treatment for primary esophageal MFS, especially in elderly high-risk patients with obvious dysphagia symptoms.

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High-grade myxofibrosarcoma of the abdominal wall

Cited by 3 publications

References 39 publications

Myxofibrosarcoma of the abdominal wall : A case report and literature review

Myxofibrosarcoma of the abdominal wall : A case report and literature review

Myxofibrosarcoma of the mandible: a case report and review of the literature

Giant myxofibrosarcoma of the esophagus treated by endoscopic submucosal dissection: A case report

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