High-Grade Transitional Cell Carcinoma and Melanosis of Urinary Bladder: Case Report and Review of the Literature

A Case of Bladder Melanosis Associated with Recurrent Urinary Tract Infections

“…A wide range of associated urinary symptoms have been described in the reported cases [3-5, 9, 12, 14], including frank hematuria [9], urinary incontinence [3,14], and recurrent UTI [5], as was present in this case. These have ranged from mild to severe and debilitating to the degree that cystoprostatectomy and neobladder formation has been carried out [4].…”

“…Bladder melanosis is thought to be benign; however, reports exist of an association with primary malignant melanoma [2] and transitional cell carcinoma [5] of the urinary bladder. In the case of transitional cell carcinoma (TCC) described by Sanborn et al, this condition was preceded by melanosis of the bladder, observed cystoscopically a year before first presentation of the TCC.…”

Prostatik Melanozis: Olgu sunumu

“…Although prostatic melanosis is incidentally found and very rare lesion , its association with prostatic acinar adenocarcinoma has been reported 1 . In literature Sharon et al has also reported a case diagnosed as melanosis of the urinary bladder and presented with transitional cell carcinoma of the bladder 1 year later 9 . However, because of the rarity and unknown course of melanosis, it might be prudent to initiate on going surveillance of patients with this condition to check for the development of urothelial or melanocytic malignancy.…”

Melanosis of the Bladder: A Case Report

“…Patient's past medical history is positive for recurrent urinary tract infections and two caesarean sections. literature to date [3][4][5][6]. Patients presented with different urinary tract symptoms such as haematuria, dysuria, incontinence and urinary tract infections [3].…”

“…Both cases show no melanocytes in the urothelium. Sanborn et al [3] described a case of a 63-year old women with melanosis of the bladder who one year later developed a transitional cell bladder carcinoma. Harikrishnan et al [5] report a case of a 50-year-old man who presented with melanosis vesica described as a diffusely pigmented bladder, without the presence of melanocytes.…”