High-Grade Undifferentiated Pleomorphic Sarcoma of the Aortic Arch: A Case of Endovascular Therapy for Embolic Prophylaxis and Review of the Literature

Abstract

Primary malignant tumors of the aorta (PMTAs) are an extremely rare clinical entity. In most cases, the diagnosis is made either postmortem or late in the course of disease due to a low index of clinical suspicion and presenting symptoms that mimic far more common athero-embolic processes. Due to the intravascular origin of these tumors, peripheral and mesenteric embolic events represent a major source of morbidity and mortality. We present the first reported case of a patient with a diagnosed PMTA treated with an endovascular aortic stent for the purpose of embolic prophylaxis. The presentation, diagnosis, classification, and management of PMTAs in the world literature are also reviewed.

2014 ESC Guidelines on the diagnosis and treatment of aortic diseases

“…Odsetek całkowitego przeżycia po 3 latach to 11,2%. Po wykonaniu resekcji chirurgicznej 3-letnie przeżycie zwiększa się do 16,5% [542].…”

Manifestation of Pleomorphic Undifferentiated Aortic Sarcoma with Splenic Infarction: A Case Report

“…By the time of diagnosis, metastasis already occurred in 80% of the patients [9]. Tumor emboli mostly involve liver, lungs, and bones [10]. Arterial embolization occurs in 46.7% of diagnosed patients [11].…”

Primary aortic sarcoma in arch and descending aorta: a case report and literature review

“…Endovascular management was then adopted to prevent recurrent thrombus. Only several literatures (14)(15)(16)(17)(18)(19) (Table 1) mentioned the use of stent for management. Zhang et al (20) adopted a palliative surgery for a patient with an intimal sarcoma, in which axillary bifemoral and femoro-femoral cross-over bypass surgeries were performed.…”