High intensity interval training reduces systemic inflammation in post-PCI patients

Munk, Peter; Breland, Unni M.; Aukrust, Pål; Ueland, Thor; Kvaløy, Jan Terje; Larsen, Alf Inge

doi:10.1177/1741826710397600

Cited by 51 publications

(64 citation statements)

References 26 publications

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“…Other medium to long HIIT protocols have been employed in the literature previously with length stages from 1 to 4 min (80% to 145% PPO) and involved mainly low-intensity active recovery (10% PPO to 70% HRmax) [27][28][29][30][31][32][33] with a close work/recovery ratio (see review [23] for details). Although as effective or even superior to CAET (see the Section 3.1), these HIIT protocols may have some limitations and most importantly were chosen arbitrarily [22,34].…”

Section: Hiit With Medium To Long Intervalsmentioning

confidence: 99%

High-intensity interval training in patients with coronary heart disease: Prescription models and perspectives

Ribeiro

Boidin

Juneau

et al. 2017

Annals of Physical and Rehabilitation Medicine

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Recently, high-intensity interval training (HIIT) has emerged as an alternative and/or complementary exercise modality to continuous aerobic exercise training (CAET) in CHD patients. However, the literature contains descriptions of many HIIT protocols with different stage durations, nature of recovery and intensities. In this review, we discuss the most recent forms of validated HIIT protocols in patients with coronary heart disease (CHD) and how to prescribe and use them during short- and long-term (phase II and III) cardiac rehabilitation programs. We also compare the superior and/or equivalent short- and long-term effects of HIIT versus CAET on aerobic fitness, cardiovascular function, and quality of life; their efficiency, safety, and tolerance; and exercise adherence. Short interval HIIT was found beneficial for CHD patients with lower aerobic fitness and would ideally be used in initiation and improvement stages. Medium and/or long interval HIIT protocols may be beneficial for CHD patients with higher aerobic fitness, and would be ideally used in the improvement and maintenance stages because of their high physiological stimulus. Finally, we propose progressive individualized models of HIIT programs (phase II to III) for patients with CHD and how to ideally use them according to the clinical status of patients and phase of the cardiac rehabilitation program.

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Section: Hiit With Medium To Long Intervalsmentioning

confidence: 99%

High-intensity interval training in patients with coronary heart disease: Prescription models and perspectives

Ribeiro

Boidin

Juneau

et al. 2017

Annals of Physical and Rehabilitation Medicine

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“…Specifically, in both healthy and clinical populations, HIT improves VO 2 peak, exercise performance, cardiovascular function, and markers of oxidative capacity in skeletal muscle [1]. HIT has also recently been reported to reduce systemic inflammation in both coronary intervention patients [2] and individuals with metabolic syndrome [3].…”

Section: Introductionmentioning

confidence: 99%

Reducing the Intensity and Volume of Interval Training Diminishes Cardiovascular Adaptation but Not Mitochondrial Biogenesis in Overweight/Obese Men

et al. 2013

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ObjectiveThe purpose of this research was to determine if the adaptations to high intensity interval training (HIT) are mitigated when both intensity and training volume (i.e. exercise energy expenditure) are reduced.Methods19 overweight/obese, sedentary males (Age: 22.7±3.9 yrs, Body Mass Index: 31.4±2.6 kg/m2, Waist Circumference: 106.5±6.6 cm) performed 9 sessions of interval training using a 1-min on, 1-min off protocol on a cycle ergometer over three weeks at either 70% (LO) or 100% (HI) peak work rate.ResultsCytochrome oxidase I protein content, cytochrome oxidase IV protein content, and citrate synthase maximal activity all demonstrated similar increases between groups with a significant effect of training for each. β-hydroxyacyl-CoA dehydrogenase maximal activity tended to increase with training but did not reach statistical significance (p = 0.07). Peroxisome proliferator-activated receptor gamma coactivator-1α and silent mating type information regulator 2 homolog 1 protein contents also increased significantly (p = 0.047), while AMP-activated protein kinase protein content decreased following the intervention (p = 0.019). VO2peak increased by 11.0±7.4% and 27.7±4.4% in the LO and HI groups respectively with significant effects of both training (p<0.001) and interaction (p = 0.027). Exercise performance improved by 8.6±7.6% in the LO group and 14.1±4.3% in the HI group with a significant effect of training and a significant difference in the improvement between groups. There were no differences in perceived enjoyment or self-efficacy between groups despite significantly lower affect scores during training in the HI group.ConclusionsWhile improvements in aerobic capacity and exercise performance were different between groups, changes in oxidative capacity were similar despite reductions in both training intensity and volume.

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“…The number of anginal episodes was also markedly lower in the rehabilitation training group, indicating that rehabilitation training could improve the exercise capacity of patients with coronary artery disease and blood circulation in the myocardium. Individualized exercise through prescribed exercise type, intensity, exercise interval and frequency can tailor to the needs of individuals and thus better promote cardiac function and prevent the progression of coronary heart disease[17]–[19]. One limitation of the current study is the low number of study subjects, which may limit the generalizability of our findings.…”

Section: Discussionmentioning

confidence: 97%

Rehabilitation training improves exercise tolerance after percutaneous coronary intervention

et al. 2012

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The aim of this present study was to investigate the effects of training on exercise tolerance of patients with coronary heart disease after percutaneous coronary intervention. Fifty-seven cases of coronary heart disease after percutaneous coronary intervention were divided randomly into the rehabilitation training group (26 cases) and control group (31 cases). Patients in the rehabilitation training group received rehabilitation training at different stages and exercise intensities 3 d after percutaneous coronary intervention for 3 months. The heart rate, blood pressure, ECG changes in treadmill exercise test, and the frequency of anginal episodes were observed. The results showed that NST and ΣST of ECG and the frequency of anginal episodes were significantly reduced in the rehabilitation training group. In addition, exercise tolerance was improved and the total exercise time was lengthened in these patients. Moreover, ST segment depression time and emergence time of angina with exercise were also lengthened compared with controls (P < 0.05, or 0.01). However, the heart rate and blood pressure before and after exercise of the two groups were similar. The study indicated that rehabilitation training could significantly relieve angina, amend ischemic features of ECG, and improve exercise tolerance of coronary heart disease patients after percutaneous coronary intervention.

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High intensity interval training reduces systemic inflammation in post-PCI patients

Abstract: Regular exercise training in stable angina patients following PCI may attenuate some, but not all, inflammatory pathways, potentially contributing to the beneficial effects of exercise training on restenosis.

Cited by 51 publications

References 26 publications

High-intensity interval training in patients with coronary heart disease: Prescription models and perspectives

High-intensity interval training in patients with coronary heart disease: Prescription models and perspectives

Reducing the Intensity and Volume of Interval Training Diminishes Cardiovascular Adaptation but Not Mitochondrial Biogenesis in Overweight/Obese Men

Rehabilitation training improves exercise tolerance after percutaneous coronary intervention

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