High-level production and extraction of C-phycocyanin from cyanobacteria Synechococcus sp. PCC7002 for antioxidation, antibacterial and lead adsorption

Lin, Jen-Lien; Tan, Shih‐I; Yi, Ying-Chen; Hsiang, Chuan-Chieh; Chang, Chien‐Hsiang; Chen, Chun‐Yen; Chang, Jo‐Shu; Ng, I‐Son

doi:10.1016/j.envres.2021.112283

Cited by 20 publications

(3 citation statements)

References 50 publications

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“…Purified phycocyanin from Synechococcus sp. displayed 89% antioxidant activity of 2,2-diphenyl-1-picryhydrazyl (DPPH) and 11% of superoxide free radical scavenging activity [30]. Another study demonstrated its proton-donating ability and a 70% scavenging capacity at a dose of 80 μg [31].…”

Section: Free Radical Scavengingmentioning

confidence: 97%

Phycocyanin, The Microalgae Bio-Treasure

Campos,

Fernandes,

Novo Barros

2024

Food Science and Nutrition

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The growing demand for natural alternatives to synthetic compounds has propelled the large-scale production of microalgae and their bioactive constituents. Among these, phycocyanin, a prominent pigment abundant in blue-green algae, has emerged as a subject of intense research interest due to its multifaceted biological activities, which include antioxidative, anti-inflammatory, anticancer, and neuroprotective properties. Its versatility has led to widespread use across various industries, from food and cosmetics to pharmaceuticals, underscoring its economic significance. As a result, efforts have been intensified to refine production processes, enhance purity, and ensure stability to increase its market value. Furthermore, the exploration of secondary metabolites derived from microalgae production holds promise for cross-industry applications, fostering industrial symbiosis and a circular economy. This chapter aims to elucidate the antioxidant capacity of phycocyanin derived from microalgae and delve into its potential for therapeutic approaches.

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Section: Free Radical Scavengingmentioning

confidence: 97%

Phycocyanin, The Microalgae Bio-Treasure

Campos,

Fernandes,

Novo Barros

2024

Food Science and Nutrition

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“…Phycocyanin is made up of a protein moiety (and apoprotein subunits) and bilin-type chromophores. Phycocyanin accounts for approximately 0.439 g/g of cyanobacteria biomass [36], but the concentration of phycocyanin in the cell is completely dependent on environmental growth conditions. Phycocyanin is thought to be an accessory pigment that absorbs light energy and transfers it to chlorophyll-a [35].…”

Section: Phycobiliproteinsmentioning

confidence: 99%

Sustainable Microalgae and Cyanobacteria Biotechnology

et al. 2022

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Marine organisms are a valuable source of new compounds, many of which have remarkable biotechnological properties, such as microalgae and cyanobacteria, which have attracted special attention to develop new industrial production routes. These organisms are a source of many biologically active molecules in nature, including antioxidants, immunostimulants, antivirals, antibiotics, hemagglutinates, polyunsaturated fatty acids, peptides, proteins, biofuels, and pigments. The use of several technologies to improve biomass production, in the first step, industrial processes schemes have been addressed with different accomplishments. It is critical to consider all steps involved in producing a bioactive valuable compound, such as species and strain selection, nutrient supply required to support productivity, type of photobioreactor, downstream processes, namely extraction, recovery, and purification. In general, two product production schemes can be mentioned; one for large amounts of product, such as biodiesel or any other biofuel and the biomass for feeding purposes; the other for when the product will be used in the human health domain, such as antivirals, antibiotics, antioxidants, etc. Several applications for microalgae have been documented. In general, the usefulness of an application for each species of microalgae is determined by growth and product production. Furthermore, the use of OMICS technologies enabled the development of a new design for human therapeutic recombinant proteins, including strain selection based on previous proteomic profiles, gene cloning, and the development of expression networks. Microalgal expression systems have an advantage over traditional microbial, plant, and mammalian expression systems for new and sustainable microalga applications, for responsible production and consumption.

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“…In addition to using the band ratio as independent variables for the input of the model, researchers have also proposed an enhanced three-band empirical model based on a three-band algorithm [17,18] framework to detect high PC concentrations (PC ∈ [68. 13,3032.47] µg/L) in inland water bodies. This algorithm experienced a significant decrease in predictive accuracy when the PC concentrations are below 300 µg/L, with the model's coefficient of determination (R 2 ) dropping from 0.99 to 0.65 [19].…”

Section: Introductionmentioning

confidence: 99%

Early Warning of Red Tide of Phaeocystis globosa Based on Phycocyanin Concentration Retrieval in Qinzhou Bay, China

Liu,

Yao,

Chen

et al. 2023

Applied Sciences

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Phaeocystis globose (P. glo) are the most frequent harmful algae responsible for red tides in Qinzhou Bay, Guangxi. They pose a significant threat to the coastal marine ecosystem, making it essential to develop an efficient indicator method tailored to P. glo outbreaks. In remote sensing water quality monitoring, there is a strong correlation between P. glo and cyanobacteria, with phycocyanin (PC) serving as an indicator of cyanobacterial biomass. Consequently, existing research has predominantly focused on remote sensing monitoring of medium to high PC concentrations. However, it is still challenging to monitor low PC concentrations. This paper introduced the BP neural network (BPNN) and particle swarm optimization algorithm (PSO). It selects spectral bands and indices sensitive to PC concentrations and constructs a PC concentration retrieval model, in combination with meteorological factors, offering a comprehensive exploration of the indicative role of low PC concentrations in predicting P. glo red tide outbreaks in Qinzhou Bay. The results demonstrated that the PC concentration retrieval model, based on the backpropagation neural network optimized by the particle swarm optimization algorithm (PSO-BPNN), demonstrated better performance (MAE = 0.469, RMSE = 0.615). In Qinzhou Bay, PC concentrations were mainly concentrated around 2~5 μg/L. During the P. glo red tide event, the area with undetectable PC concentrations (PC < 0.04 μg/L) increased by 4.97 km2, with regions below 0.9 μg/L experiencing exponential growth. Considering the variations in PC concentrations along with meteorological factors, we proposed a straightforward early warning threshold for P. glo red tides: PC < 0.9 μg/L and T < 20 °C. This method, from a remote sensing perspective, analyzes the process of P. glo outbreaks, simplifies PC concentration monitoring, and provides a reasonably accurate prediction of the risk of P. glo red tide disasters.

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High-level production and extraction of C-phycocyanin from cyanobacteria Synechococcus sp. PCC7002 for antioxidation, antibacterial and lead adsorption

Cited by 20 publications

References 50 publications

Phycocyanin, The Microalgae Bio-Treasure

Phycocyanin, The Microalgae Bio-Treasure

Sustainable Microalgae and Cyanobacteria Biotechnology

Early Warning of Red Tide of Phaeocystis globosa Based on Phycocyanin Concentration Retrieval in Qinzhou Bay, China

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