“…Namely, its impact varies widely from region to region and its ubiquitous nature is often associated with diseases for which a causative link cannot be established. It should be noted that in controlled experimental trials, PRV has (as yet) never caused clinical morbidity or mortality in salmon even during extreme blood infections (Garver, Johnson, et al, 2016; Polinski et al., 2019; Purcell et al., 2020; Takano et al., 2016; Wessel et al., 2017), nor has it contributed to clinical morbidity or mortality during experimental trials in accompaniment with stressors such as smoltification, viral co‐infection, hypoxia, or exhaustive chasing (Garver, Johnson, et al, 2016; Lund et al., 2016, 2017; Polinski et al., 2016; Zhang et al., 2019). However, this does not negate the fact that all three genogroups of PRV can at the very least cause mild to moderate disease in an experimental setting and almost certainly contribute to clinical disease states in farmed salmon stocks, which in some situations result in significant morbidity or mortality (Olsen et al., 2015; Takano et al., 2016; Vendramin, Kannimuthu, et al, 2019; Wessel et al., 2017).…”