A comparative study of major elements, trace elements, and isotopes in high-and moderate-Mg volcanic sequences of 16-14 and 14-13 Ma, respectively, has been performed in the Bereya volcanic center. In the former (small volume) sequence, contaminated by crustal material basalts and trachybasalts of K-Na series were followed by uncontaminated basanites and basalts of transitional (K-Na-K) compositions and afterwards by picrobasalts and basalts of K series. From pressure estimates using equation [Scarrow, Cox, 1995], high-Mg magma originated at the deep range of 115-150 km. In the latter (high-volume) sequence, basalts and basaltic andesites of transitional (Na-K-Na) compositions and basalts of Na series were overlain by basalts and trachybasalts of K-Na series. First, there was a strong melting of its shallow garnet-free part with coeval weak melting of more deep garnet-bearing portion, then only a deep garnet-bearing portion of the lithospheric mantle melted. It is suggested that the sequential formation of high-and moderate-Mg melts reflected the mid-Miocene thermal impact of the lithosphere by hot material from the Transbaikalian low-velocity domain, which had the potential temperature Tp as high as 1510 °С. This thermal impact triggered the rifting in the lithosphere of the Baikal Rift System.