High minimum inhibitory concentrations among derepressed AmpC-beta-lactamase–producing Enterobacter cloacae complex isolates for ceftolozane with tazobactam

Abstract

first steps in environmentally compatible fly control and will provide long-term discouragement of additional pest invaders. I recommend the following systematic approach: (1) prioritized leadership and hospital administrative commitment to sanitation; (2) empowering and educating food service workers in illness prevention; (3) emphasizing environmentally compatible sanitation methods coupled with strategic and specific applications of antipest agents when required; and (4) looking beyond surface cleanliness to follow food as an attractor of pests. Acknowledgments. Kurt C. Stange, MD, PhD, provided helpful guidance in writing this commentary. Financial support. No financial support was provided relevant to this article.

Cefazolin and Imipenem Enhance AmpC Expression and Resistance in NagZ-Dependent Manner in Enterobacter Cloacae

“…Among Enterobacter cloacae complex, EC is isolated very frequently from clinical specimens obtained from humans as well as medical devices and takes on clinical signi cance to intensive care patients in the past decade, particularly to the patients put on mechanical ventilation [2]. The antibioticresistance characteristics of microorganisms, for instance, EC has been a point of focus of quite a large number of publications [3][4][5]. EC is inherently resistant to amoxicillin, ampicillin, 1st-and 2nd-generation of cephalosporin, and cefoxitin on account of the generation of inducible chromosomes AmpC β-lactamase (AmpC) [6].…”