High-order brain interactions in ketamine during rest and task:
A double-blinded cross-over design using portable EEG
Agustin Ibanez,
Ruben Herzog,
Florentine Barbey
et al.
Abstract:Methods
In a double-blinded cross-over design, 30 adults (mean age = 25.57, SD = 3.74; all male) were administered racemic ketamine and compared against saline infusion as a control. Both task-driven (auditory oddball paradigm) and resting-state EEG were recorded. HOI were computed using advanced multivariate information theory tools, allowing us to quantify nonlinear statistical dependencies between all possible electrode combinations. Results: Ketamine increased redundancy in brain dynamics, most significan… Show more
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