High-performance liquid chromatography of chromonoid compounds

Determination of Chromones in Dysophylla stellata by HPLC: Method Development, Validation and Comparison of Different Extraction Methods

“…Because of their pharmaceutical importance, researchers have reported the analysis of chromones in plants and biological samples. Borda et al [12] studied the effect of substituents on the retention time of synthetic chromones by HPLC. HPLC/MS and HPLC/MS/MS methods have also been used for analysis of chromones in plant extracts [13,14], as well as in rat plasma and urine [15] We have reported the COX-1/COX-2 inhibitory and antiinflammatory activities of chromones from D. stellata and found that stellatin, in particular, could be responsible for these [16].…”