The droplet electricity generator (DEG) is a solid‐liquid triboelectric nanogenerator (TENG) with transistor‐inspired bulk effect, which is regarded as an effective strategy for raindrop energy harvesting. However, further enhancement of DEG output voltage is necessary to enable its widespread applications. In this work, high‐entropy ceramics are integrated into the design of DEG intermediate layer for the first time, achieving a high output voltage of 525 V. High‐entropy ceramics have colossal dielectric constant, which can help to reduce the triboelectric charge decay for DEG. Furthermore, we extensively analyze the effect of factors on DEG output performance when employing high‐entropy ceramics as the intermediate layer, and explore the underlying mechanisms and mathematical models. Lastly, the enhanced output voltage of DEG not only facilitates faster energy harvesting but also enables a novel method for rapid bacterial detection. This work successfully integrates high‐entropy ceramics into DEG design, significantly enhances the output voltage and offers a novel direction for DEG development.This article is protected by copyright. All rights reserved