We review the field we describe as "single-mode fiber optofluidics" which combines the technologies of microfluidics with single-mode fiber optics for delivering new implementations of well-known single-mode optical fiber devices. The ability of a fluid to be easily shaped to different geometries plus the ability to have its optical properties easily changed via concentration changes or an applied electrical or magnetic field offers potential benefits such as no mechanical moving parts, miniaturization, increased sensitivity and lower costs. However, device fabrication and operation can be more complex than in established singlemode fiber optic devices. . Her research areas include optofluidic devices and applications.Deepak Uttamchandani (SM'05) received his PhD degree from University College London, London, UK in 1985 for research in the areas of optical fiber sensors and optical frequency domain reflectometry. He is currently the Head of the Centre for Microsystems and Photonics, University of Strathclyde, Glasgow, UK. His early research in MEMS concentrated on opto-thermal microresonator sensors and in investigating techniques for MEMS material characterization using micromechanical resonators. His recent research has concentrated on system applications of optical MEMS including intra-cavity MEMS-based laser systems, MEMS-based directional microphones and MEMS-based single-pixel imaging systems. He has also published in the fields of optofluidic devices, optical sensors, including sub-wavelength tipbased Raman spectroscopy, and in situ intraocular drug detection systems via optical spectroscopy in the eye. In 2014 he organized and chaired the IEEE Optical MEMS and Nanophotonics conference (Glasgow, UK)..