High-pressure steam sterilization of previously used CIDR inserts enhances the magnitude of the acute increase in circulating progesterone after insertion in cows

Zuluaga, J.F.; Williams, Gary L.

doi:10.1016/j.anireprosci.2007.06.006

Cited by 30 publications

(39 citation statements)

References 17 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Moreover, CIDR devices achieved 2.3 and 1.9 ng/ mL blood P 4 in ovariectomized cows on days 14 and 15 relative to insertion (14). However, P 4 concentration at a minimum of 1 ng/mL is needed to block LH surge release (5). Moreover, using a CIDR device up to 21 days still releases P 4 at a sufficient level to suppress estrus and induce synchronization.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Efficacy of repeatedly used CIDR device in cattle reproduction: a metaanalysisreview of progesterone concentration and conception rate

Chacher¹,

Çolak²,

Hayırlı³

2017

Turk J Vet Anim Sci

View full text Add to dashboard Cite

In order to reduce estrus synchronization cost, utilization of residual progesterone (P 4 ) in the used controlled internal drug release (CIDR) device upon sanitization can be possible. Two datasets were compiled from 8 and 7 research articles involving 3434 (2653 heifers + 771 lactating cows + 10 ovariectomized cows) and 7301 cattle (3879 heifers + 3422 lactating cows) to evaluate blood P 4 concentration and conception rate, respectively, in response to repeatedly used CIDR devices after sanitization via autoclaving and disinfection. As the number of CIDR usages increased, blood P 4 concentration decreased linearly (y = -0.484X + 3.135, R 2 = 0.99, P < 0.001). Blood P4 concentration (1.52 vs. 2.20 ng/mL; P < 0.002) and conception rate (40.76 vs. 32.96%, P < 0.05) for lactating cows were lower than those for heifers. The sanitization method did not affect blood P4 concentration, but reused CIDR device subjected to disinfection was associated with reduced conception rate. In summary, depending upon the initial P4 load (1.38-1.90 g), the CIDR device could be used twice in lactating cows and four times in heifers after autoclaving to achieve target blood P4 concentrations.

show abstract

Section: Introductionmentioning

confidence: 99%

“…The controlled internal drug release (CIDR) device is an intravaginal insert that acts as a P 4 source to maintain the blood P 4 concentration (5,6). The CIDR device is a T-shaped device having a nylon spine molded by silicon rubber skin impregnated by either 1.90 or 1.38 g of P 4 (7).…”

Section: Introductionmentioning

confidence: 99%

Efficacy of repeatedly used CIDR device in cattle reproduction: a metaanalysisreview of progesterone concentration and conception rate

Chacher¹,

Çolak²,

Hayırlı³

2017

Turk J Vet Anim Sci

View full text Add to dashboard Cite

show abstract

“…Several reports compared the progesterone concentration achieved after insertion of new or once or more reused CIDR (Zuluaga and Williams, 2008;Long et al, 2009;Carvalho et al, 2014). Additionally, the efficiency of the estradiol-progestin based synchronization protocols after incorporating once or more reused CIDR had been investigated in bovine (Colazo et al, 2004;Colazo et al, 2006;Meneghetti et al, 2009;Carvalho et al, 2014) or small ruminant (Vilariño et al, 2011;Vilariño et al, 2013).…”

Section: Introductionmentioning

confidence: 99%

“…Reused CIDR can be a source of microbial transmission among cows; therefore intensive sterilization process is indicated (Zuluaga and Williams, 2008). Reusing the CIDR in the same animal will eliminate the possibility of microbial transmission.…”

Section: Introductionmentioning

confidence: 99%

Efficiency of Previously used CIDR Stored for a Prolonged Period

Abdallah¹,

Elrahim²

2014

Adv. Anim. Vet. Sci.

View full text Add to dashboard Cite

| This study investigated the efficiency of the previously used controlled internal drug release (CIDR) stored for 30 days before reusing. In the first experiment, twenty seven Holstein cows at the day of estrus (day 0) received either no treatment (control), new or reused CIDR and blood samples were collected at day 0, 1, 3 and 7. At day 1 and 3, serum progesterone concentration in cows received new CIDR (1.417 and 1.616 ng/ml) was significantly higher than in cows received a reused one (0.545 and 0.954 ng/ml) which in turn was higher than the control group. In the second experiment, estrous cycle was synchronized using Ovsynch, New-CIDRsynch or Reused-CIDRsynch. Cows in Ovsynch (n=119) received GnRH on day 0 then PGF2α on day 7. Fifty six hours after the PGF2α cows received another dose from GnRH and inseminated 18 h latter. Cows in new-CIDRsynch (n=870) and reused-CIDRsynch (n=220) were treated in the same way with exception of inserting a new or reused CIDR between day 0 and day 7. Non returned cows were examined for pregnancy diagnosis at 30 and 70 days post-insemination. Pregnancy-30 and 70 rates after New-CIDRsynch (36.1% and 30.5%) and Reused-CIDRsynch (36.4% and 31.8%) tended to be higher than after Ovsynch (27.7% and 25.2%) (P= 0.07: 0.08). In conclusion, the previously used CIDR -stored for 30 days-have residual progesterone and incorporating new or reused CIDR into Ovsynch improved the efficiency of the protocol in a similar way.

show abstract

“…Because these devices are discarded after use, this can be a source of economic loss. These devices have been reused recently in cows, and researchers report successful results 8, 9 . However, there have been no reports of similar trials in ewes and goats.…”

Section: Introductionmentioning

confidence: 99%

Koyunlarda Anöstrus Mevsiminde Kullanılmış CIDR-G Uygulamasıyla Östrusun Uyarılması

Güngör¹,

Özyurtlu²,

Pancarcı³

et al. 2009

Kafkas Univ Vet Fak Derg

View full text Add to dashboard Cite

High-pressure steam sterilization of previously used CIDR inserts enhances the magnitude of the acute increase in circulating progesterone after insertion in cows

Cited by 30 publications

References 17 publications

Efficacy of repeatedly used CIDR device in cattle reproduction: a metaanalysisreview of progesterone concentration and conception rate

Efficacy of repeatedly used CIDR device in cattle reproduction: a metaanalysisreview of progesterone concentration and conception rate

Efficiency of Previously used CIDR Stored for a Prolonged Period

Koyunlarda Anöstrus Mevsiminde Kullanılmış CIDR-G Uygulamasıyla Östrusun Uyarılması

Contact Info

Product

Resources

About