High prevalence and pathogenic potential of Shiga toxin-producing Escherichia coli strains in raw mutton and beef in Shandong, China

Hu, Bin; Yang, Xi; Liu, Qian; Zhang, Yuanqing; Jiang, Deshui; Jiao, Hongbo; Yang, Ying; Xiong, Yanwen; Bai, Xiangning; Hou, Peibin

doi:10.1016/j.crfs.2022.08.021

Cited by 6 publications

(4 citation statements)

References 49 publications

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“…biortech. 2019.122425 Xian, Z., Wu, J., Deng, M., Wang, M., Tian, H., Liu, D., et al (2022). Effects of cellulase and Lactiplantibacillus plantarum on the fermentation parameters, nutrients, and bacterial community in Cassia alata silage.…”

Section: Discussionmentioning

confidence: 99%

One-Health meets microbiota: Interactions between digestive tract microbiota, host, and environment

2024

Frontiers Research Topics

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Frontiers is more than just an open access publisher of scholarly articles: it is a pioneering approach to the world of academia, radically improving the way scholarly research is managed. The grand vision of Frontiers is a world where all people have an equal opportunity to seek, share and generate knowledge. Frontiers provides immediate and permanent online open access to all its publications, but this alone is not enough to realize our grand goals. Frontiers journal seriesThe Frontiers journal series is a multi-tier and interdisciplinary set of openaccess, online journals, promising a paradigm shift from the current review, selection and dissemination processes in academic publishing. All Frontiers journals are driven by researchers for researchers; therefore, they constitute a service to the scholarly community. At the same time, the Frontiers journal series operates on a revolutionary invention, the tiered publishing system, initially addressing specific communities of scholars, and gradually climbing up to broader public understanding, thus serving the interests of the lay society, too. Dedication to qualityEach Frontiers article is a landmark of the highest quality, thanks to genuinely collaborative interactions between authors and review editors, who include some of the world's best academicians. Research must be certified by peers before entering a stream of knowledge that may eventually reach the public -and shape society; therefore, Frontiers only applies the most rigorous and unbiased reviews. Frontiers revolutionizes research publishing by freely delivering the most outstanding research, evaluated with no bias from both the academic and social point of view. By applying the most advanced information technologies, Frontiers is catapulting scholarly publishing into a new generation. What are Frontiers Research Topics?Frontiers Research Topics are very popular trademarks of the Frontiers journals series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area.

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Section: Discussionmentioning

confidence: 99%

One-Health meets microbiota: Interactions between digestive tract microbiota, host, and environment

2024

Frontiers Research Topics

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“…Non-O157 STEC isolated from diarrheal patients in China were dominated by the stx1c subtype [41], which is accordant with our stx subtype from asymptomatic food handlers. Several studies depicted the prevalence and characteristics of STEC strains in retail raw meats in China, showing that stx1c and stx2e were predominant subtypes [51,52]. They could serve as a reservoir for the dissemination of virulence genes through the food chain.…”

Section: Discussionmentioning

confidence: 99%

Characteristics of Shiga Toxin-Producing Escherichia coli Circulating in Asymptomatic Food Handlers

Sui,

Yang,

Luo

et al. 2023

Toxins

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Shiga toxin-producing Escherichia coli (STEC) is a foodborne zoonotic pathogen that causes diarrhea, hemorrhagic colitis (HC), and hemolytic uremic syndrome (HUS) worldwide. Since the infection can be asymptomatic, the circulation of STEC in some asymptomatic carriers, especially in healthy-food-related professionals, is not yet well understood. In this study, a total of 3987 anal swab samples from asymptomatic food handlers were collected, and ten swabs recovered STEC strains (0.251%). Of the ten STEC isolates, seven serotypes and eight sequence types (ST) were determined using whole genome sequencing (WGS). Two stx1 subtypes (stx1a and stx1c) and four stx2 subtypes (stx2a, stx2b, stx2d, and stx2e) were detected. Seven different insertion sites were found in fourteen Stx prophages, and the dmsB and yfhL were the newly identified insertion sites. The ten strains showed the variable Stx transcription levels after the mitomycin C induction. The whole-genome phylogeny indicated that the strains from the asymptomatic food handlers were genetically distant from the strains of HUS patients. The STEC isolates circulating in asymptomatic carriers might pose a low potential to cause disease.

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“…STEC is important for red meat production due to its potential to cause serious diseases that can progress from simple diarrhea to HC, HUS, end-stage renal failure and death (Cody et al, 2019). 2019 Although cattle are considered to be the main reservoir for STEC and EPEC strains, the presence of STEC and EPEC strains in sheep is not negligible (Ferhat et al, 2019;Hu et al, 2022). Determination of the main virulence factors in sheep, which are asymptomatic carriers of STEC strains, may elucidate the epidemiology and pathology of foodborne STEC infections in humans.…”

Section: Discussionmentioning

confidence: 99%

Investigation of virulence factors of shiga toxin-producing Escherichia coli strains isolated from sheep

ŞAHİN,

YILDIRIM,

KIZIL

2023

Etlik Veteriner Mikrobiyoloji Dergisi

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All over the world, Escherichia coli (STEC), which produces Shiga toxin, is recognized as an important zoonotic pathogen. Ruminants, particularly cattle, are their main reservoirs, but the role of small ruminants in the epidemiology of human infections has not been extensively evaluated in many countries. In this study, it was aimed to determine the Shiga toxin subtypes of Stx1, Stx2, eae and ehxa genes of Shiga toxin producing isolates within Escherichia coli strains in sheep and to determine the comparative effect of variables such as race and sex on them. In this study, virulence genes of STEC strains and Shiga toxin subtypes were identified in 215 E. coli isolates isolated from 272 rectal swab from 12 different sheep herds in and around Ankara. Of the 215 isolates, only 19 (8.84%) Stx1, 3 (1.4%) Stx2, 5 (2.33%) eae and 9 (4.19%) ehxa genes, 13 (6%, 05) Stx1-Stx2-ehxa, 5 (2.33%) Stx1-eae -ehxa, 3 (1.4%) Stx2-eae-ehxa together and 1 (0.47%) Stx1- eae, 30 (13.95%) Stx1- ehxa, 1 (0.47%) Stx2- eae, 15 (6.98%) Stx2-ehxa and 10 (4.65%) eae – ehxa were detected together. Of the 101 (46.98%) isolates, none of the Stx1, Stx2, eae and ehxa genes were detected. In stx1 subtyping in sheep, a high rate (82.35%) of stx1c was isolated. In stx2 subtyping stx2f (%62,86), stx2c (%54,29), stx2b (%45,71), stx2d (%22,86), stx2h (%22,86) subtypes are more common in different combinations. Detected at a high rate. These data indicate the presence of STEC in sheep and their potential to cause serious infection in humans

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High prevalence and pathogenic potential of Shiga toxin-producing Escherichia coli strains in raw mutton and beef in Shandong, China

Cited by 6 publications

References 49 publications

One-Health meets microbiota: Interactions between digestive tract microbiota, host, and environment

One-Health meets microbiota: Interactions between digestive tract microbiota, host, and environment

Characteristics of Shiga Toxin-Producing Escherichia coli Circulating in Asymptomatic Food Handlers

Investigation of virulence factors of shiga toxin-producing Escherichia coli strains isolated from sheep

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