High prevalence of cardiovascular risk in patients with toxic oil syndrome: A comparative study using the general Spanish population

Potential role of serum amyloid A in hidradenitis suppurativa

“…Assigned therapies were very heterogeneous. Two patients showed an improvement in renal function in 4 to 14 weeks of treatment with infliximab (5 mg/kg)4, 9; one patient showed an improvement in renal function after 24 weeks of clindamycin, 600 mg/d, and prednisone, 50 mg/d, 7 another patient showed a systemic improvement after treatment with adalimumab and fludrocortisone 5 . All the other patients had kidney failure 2, 3, 4, 5, 6, 7, 8…”

“…We found eight cases reported in the literature on amyloidosis and HS in the last decades2, 3, 4, 5, 6, 7, 8, 9 (Table I); none of the patients had presented with subclinical amyloidosis. All patients were between 39 and 62 years and had chronic HS of variable duration, from 3 to 25 years.…”

“…AA amyloidosis in HS has been rarely reported2, 3, 4, 5, 6, 7, 8, 9; however, AA amyloidosis related to other chronic inflammatory diseases has been well described. The deposition of AA may induce damage to viscera, connective tissue, and blood vessel walls, with the kidney as a major target.…”

Is Insulin Resistance Work Related?

“…Non-accidental occupational exposure in cohorts from 12 different countries also confirmed the relationship [163]. Bisphenol A is also a POP, well known for its endocrine disruptor effects; besides other negative effects, the rate of gestational diabetes is increased in women with a higher blood level [164]. Toxic oil syndromeregistered patients have threefold increase in prevalence of diabetes, and higher incidence of metabolic syndrome [165,166].…”

“…Sedentary behaviour has benefited from different ergonomically interventions [162,163]. Some studies have emphasized the benefit of sitting interruption during the working day; efficiency of short 1-2 min every half hour of sitting break was better in terms of metabolic syndrome criteria compared to the two 15 min breaks per workday [164]. In certain circumstances, cumulative risk factors are encountered: for example, seafarers are recognized as a profession with high incidence of metabolic syndrome.…”