High Prevalence of Hepatitis B Virus Infection in the Age Range of 20-39 Years Old Individuals in Lome

Kolou, M; Katawa, Gnatoulma; Salou, Mounérou; Gozo-Akakpo, Komlan Selom; Dossim, Sika; Kwarteng, Alexander; Prince-David, Mireille

doi:10.2174/1874357901710011001

Cited by 32 publications

(27 citation statements)

References 27 publications

(36 reference statements)

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“…In this study, the overall seropositivity of HBV infection was 6.4%, with rst time donors recording a seropositivity of 8.8%. This "high intermediate category" observation on the overall seropositivity is lower than the reports of studies in other African countries including Ghana (7.5% and 13.3%), Equatorial Guinea (10.01%), Cameroon (12.6%),Burkina Faso (14.47%), and Togo (19.08%) [9,[14][15][16][17][18]. Our ndings are, nonetheless, higher than the recorded seroprevalence of 4.1% and 3.21 that was reported in respectively, Northwest Ethiopia and Madagascar (19)(20).…”

Section: Discussionmentioning

confidence: 58%

Knowledge, attitude and seropositivity of hepatitis B virus among blood donors in the Bamenda Regional Hospital Blood Bank, Cameroon

Samje

Sop

Tayou

et al. 2020

Preprint

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Background Despite the existence of a preventive vaccine against hepatitis B viral (HBV) infection, approximately 250 million people are infected with the virus worldwide. Considering the burden of this infection, this study aimed at evaluating the level of knowledge, attitude and seropositivity of the disease among apparently healthy, potential blood donors at the blood service of the Bamenda Regional Hospital Blood Bank. Methods A cross sectional study was carried out from March to May 2019 among 250 blood donors. Following screening for Hepatitis B surface antigen (HBsAg) using the One step HBsAg test strip, information on the level of knowledge and attitude towards the infection was obtained using a self-administered questionnaire. Responses were graded as adequate knowledge or positive attitude if a cumulative score of > 50% was attained. Data was analyzed using the software IBM SPSS version 21.0. Multiple linear regression analysis was carried out to assess relationships between selected factors and knowledge of Hepatitis B. p-value of 0.05 was considered as statistical significance. Results The seropositivity of HBV was 6.4%. Overall, 46.8% of the study participants had adequate knowledge while 76.3% had a positive attitude toward the disease. The highest seropositivity was observed in singles (7.1%), primary school leavers (14.3%), unskilled laborers (14.5%) and replacement donors (9.33%). The risk of being hepatitis B seropositive was higher in males as compared to females [OR: 3.1 (95% CI 0.7–14). Participants with previous blood donation history were more protected [OR:0.4 (95% CI 0.1–1.2), p = 0.130] compared to first time donors. Conclusion The prevalence of hepatitis B among blood donors in this blood service is in the high intermediate category. On the whole, the level of knowledge on this infection among these blood donors is average. These findings suggest that health education on HBV infection should be provided to the public as a major strategy to curb the infection.

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Section: Discussionmentioning

confidence: 58%

Knowledge, attitude and seropositivity of hepatitis B virus among blood donors in the Bamenda Regional Hospital Blood Bank, Cameroon

Samje

Sop

Tayou

et al. 2020

Preprint

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“…That association was found in a survey in northern Uganda where females were more infected than males [19]. A previous study in Lomé reported that men were more infected than women [20].…”

Section: Discussionmentioning

confidence: 59%

Prevalence of Hepatitis B Surface Antigen and Hepatitis C Antibodies in Sickle Cell Disease Children under Sixteen in Two University Hospitals of Lome

Dossim

Guedenon

Chick

et al. 2020

MRJI

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Introduction: Sickle cell disease causes chronic anemia with the need for transfusions. The risk in children to get transfusions transmitted infections is high. Aims: Determine the prevalence of HBsAg and HCV antibodies in sickle cell disease children under sixteen in Lome (Togo). Study Design: It is a cross-sectional study. Place and Duration of Study: Sample: Haematology Unit of Campus University Hospital and Paediatric Unit of Sylvanus Olympio University Hospital of Lomé collected between February to May 2016. Sample processing: Campus Hospital Laboratory. Methodology: We collected blood in sickle cell disease patients in Campus and Sylvanus Olympio university hospitals at Lomé and informations about sickle cell type, transfusion, and hepatitis B vaccination. Sera were tested with Cobas e411 Roche® in the determining of hepatitis B surface antigen (HbSAg) and hepatitis C antibodies (HCVAb). Epi Info was used for statiscal analysis ®. Significant associations were found when P<0.05. Results: Total of 172 patients from Campus Hospital and 79 from Sylvanus Olympio were included. Sex ratio and SS phenotype were 0.93, 69.8% and 1.32, 64.5% respectively. HBsAg was detected in 1.7% from Campus and 7.6% in Sylvanus Olympio. One patient from Campus carried HCVAb. Significant association between hepatitis B and sex (P=0.02) and hepatitis B and vaccination were found (P= 0.0003). Males were more infected and patients who were unvaccinated carried HBsAg. Conclusion: Vaccination against viral hepatitis and best blood donation screening are necessary to avoid these viral diseases in sickle cell disease children.

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“…Many studies have already reported a higher prevalence of HBV in men compared to women [13] [20] [21]. In Lemoine's study, the prevalence of hepatitis B among men was 10.5% compared to 7.6% among women (p = 0.004).…”

Section: Discussionmentioning

confidence: 93%

“…One study conducted among people living with HIV in 2011 estimated the HBV prevalence at 9.7% [4]. Another study among prisoners in 2013 estimated the prevalence at 12.5%, while a study among individuals in a hospital in Lomé found a prevalence as high as 19.1% [5] [13]. However, no study in Togo has so far specifically focused on the prevalence of HBV among youth and university students, who could be considered a vulnerable population.…”

Section: Introductionmentioning

confidence: 99%

Prevalence of Hepatitis B among Students from the University of Lomé, Togo in 2015

Ekouévi¹,

Thomas²,

Dieudonné³

et al. 2017

OJEpi

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Objective: Hepatitis B virus (HBV) is endemic in sub-Saharan Africa where more than 80 million subjects are chronic carriers. However, screening is not systematic in the population and prevalence data are scarce, especially among the youth population. The objective of this study was to estimate the prevalence of HBV and its correlates among first-year University students at the University of Lomé. Study design: A cross-sectional survey was conducted between November 2015 and January 2016 at the University of Lomé during the annual checkup offered to newly enrolled students. Method: A self-administered questionnaire was used to collect data on demographics and sexual behaviors, and rapid tests were used for the detection of Antigen HB S (HBsAg) and HIV in each participant. A logistic regression model was performed to identify factors associated with HBsAg positivity. Results: A total of 800 students (56.2% were men) were screened among 1505 students who participated in the study. The median age was 20 years (IQR: [18 -21]). The overall prevalence of HBsAg was 4.6% (95% CI: [3.2 -6.3]): 5.8% among men and 3.1% among women (p = 0.04). The prevalence of HIV was 0.8; 95%CI [0.3% -1.6%] and one case (0.1%) of coinfection HIV and HBV was identified. Factors associated with HBsAg positivity were male gender [adjusted Odds Ratio (aOR) = 2.08, 95% CI: 1.02 -5.00, p = 0.0447] and ever having a sexual relationship [aOR = 2.44; 95% CI = 1.11 -5.78, p= 0.0264]. Conclusion: This study among university students demonstrates that the prevalence of HBV is high among this population and that there is a need for prevention programs to target this vulnerable population. This is an additional argument How to cite this paper:

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High Prevalence of Hepatitis B Virus Infection in the Age Range of 20-39 Years Old Individuals in Lome

Cited by 32 publications

References 27 publications

Knowledge, attitude and seropositivity of hepatitis B virus among blood donors in the Bamenda Regional Hospital Blood Bank, Cameroon

Knowledge, attitude and seropositivity of hepatitis B virus among blood donors in the Bamenda Regional Hospital Blood Bank, Cameroon

Prevalence of Hepatitis B Surface Antigen and Hepatitis C Antibodies in Sickle Cell Disease Children under Sixteen in Two University Hospitals of Lome

Prevalence of Hepatitis B among Students from the University of Lomé, Togo in 2015

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High Prevalence of Hepatitis B Virus Infection in the Age Range of 20-39 Years Old Individuals in Lome

Cited by 32 publications

References 27 publications

Knowledge, attitude and seropositivity of hepatitis B virus among blood donors in the Bamenda Regional Hospital Blood Bank, Cameroon

Knowledge, attitude and seropositivity of hepatitis B virus among blood donors in the Bamenda Regional Hospital Blood Bank, Cameroon

Prevalence of Hepatitis B Surface Antigen and Hepatitis C Antibodies in Sickle Cell Disease Children under Sixteen in Two University Hospitals of Lome

Prevalence of Hepatitis B among Students from the University of Lom&#233;, Togo in 2015

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Prevalence of Hepatitis B among Students from the University of Lomé, Togo in 2015