High Prevalence of <i>Toxoplasma gondii</i> Infection in Miners: A Case-Control Study in Rural Durango, Mexico

Alvarado‐Esquivel, Cosme; Pacheco-Vega, Sandy Janet; Hernández‐Tinoco, Jesús; Berumen-Segovia, Luis Omar; Sánchez‐Anguiano, Luis Francisco; Estrada-Martínez, Sergio; Sandoval-Carrillo, Ada Agustina; Salas-Pacheco, José M.; Liesenfeld, Oliver; Antuna-Salcido, Elizabeth Irasema

doi:10.14740/jocmr2789w

Cited by 3 publications

(4 citation statements)

References 26 publications

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“…gondii infection in the subset of people from rural areas observed in our present study might have contributed to an increase in the general seroprevalence. However, the seroprevalence found in people with alcohol consumption is lower than those found in other population groups in our region, including waste pickers (21.1%) [ 23 ], schizophrenic patients (20%) [ 24 ], inmates (21.1%) [ 25 ], or miners (60%) [ 26 ]. This relatively low seroprevalence found in our study coincides with the finding of a study of the Finnish general population, where researchers found that T .…”

Section: Discussionmentioning

confidence: 77%

“…The questionnaire was used as a method for recording simple variables as age, gender, etc. The questionnaire has been used in a number of epidemiological studies in the same language in the same country [13,14,18,[21][22][23][24][25][26]. Items of housing variables were previously validated [27].…”

Section: Data Collection and Socio-demographic Clinical Behavioral And Housing Variables Of Participantsmentioning

confidence: 99%

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Seroepidemiology of Toxoplasma gondii infection in people with alcohol consumption in Durango, Mexico

Estrada-Martínez¹,

Pérez-Álamos²,

Ibarra-Segovia

et al. 2021

PLoS ONE

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The seroepidemiology of infection with Toxoplasma gondii (T. gondii) in alcohol consumers is largely undeveloped. In light of this, we sought to determine the seroprevalence of T. gondii infection in alcohol consumers in Durango, Mexico, and the association of T. gondii seroprevalence with characteristics of the population studied. Anti-T. gondii IgG and IgM antibodies were searched in sera of participants using commercially available enzyme immunoassays. Bivariate and logistic regression analyses were then used to determine the association between T. gondii infection and the characteristics of the population studied. Of the 1544 people studied (mean age: 39.4±14.0 years), 173 (11.2%) tested positive for anti-T. gondii IgG antibodies. We were able to test 167 of the 173 anti-T. gondii IgG positive sera for anti-T. gondii IgM antibodies. Fifty-five (32.9%) of these 167 serum samples were positive for anti-T. gondii IgM antibodies. Bivariate analysis showed that visual impairment, history of surgery, and hepatitis were negatively associated with T. gondii IgG seropositivity (P<0.05). In women, seropositivity to T. gondii was positively associated with a history of pregnancy (P<0.05). Logistic regression analysis showed that T. gondii seropositivity was associated with the variables consumption of armadillo meat (OR = 2.33; 95% CI: 1.04–5.22; P = 0.03), and the use of latrines for elimination of excretes (OR = 2.27; 95% CI: 1.07–4.80; P = 0.03); and high (>150 IU/ml) anti-T. gondii IgG antibodies were associated with consumption of both armadillo meat (OR = 2.25; 95% CI: 1.01–5.02; P = 0.04) and crowding at home (OR = 1.63; 95% CI: 1.02–2.61; P = 0.03). We found a distinct T. gondii seroprevalence in people with alcohol consumption from those previously found in population groups in the region. This is the first study that illustrates the association between high anti-T. gondii antibodies and crowding in Mexico, and the second study on the association between T. gondii infection and consumption of armadillo meat and the use of latrines in this country. We conclude that epidemiology of T. gondii infection in people with alcohol consumption deserves further investigation.

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Section: Discussionmentioning

confidence: 77%

Section: Data Collection and Socio-demographic Clinical Behavioral And Housing Variables Of Participantsmentioning

confidence: 99%

Seroepidemiology of Toxoplasma gondii infection in people with alcohol consumption in Durango, Mexico

Estrada-Martínez¹,

Pérez-Álamos²,

Ibarra-Segovia

et al. 2021

PLoS ONE

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“… 21 However, there are specific population groups in Mexico with a high seroprevalence of T. gondii infection; for instance, miners in Durango State who had a seroprevalence of 60%. 22 We looked for sociodemographic, behavioural and housing characteristics associated with T. gondii seropositivity. Logistic regression analysis showed that T. gondii infection was positively associated with availability of potable water at street, and negatively associated with being born in Mexico.…”

Section: Discussionmentioning

confidence: 99%

Toxoplasma gondiiinfection in pregnant women: a cross-sectional study in Matehuala City, Mexico

et al. 2020

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ObjectivesThis study aimed to determine the seroprevalence of Toxoplasma gondii (T. gondii) infection in pregnant women in Matehuala City, Mexico; and the associated risk factors.DesignA cross-sectional study.SettingMatehuala City, Mexico.Participants311 pregnant women.Primary and secondary outcome measuresSera of women were analysed for anti-T. gondii IgG and IgM antibodies by commercially available immunoassays. Bivariate and multivariate analyses were used to assess the association between T. gondii seroprevalence and the characteristics of the pregnant women.ResultsThirteen (4.2%) of the 311 pregnant women studied were positive for anti-T. gondii IgG antibodies. No anti-T. gondii IgM antibodies were found in anti-T. gondii IgG seropositive women. No association between seropositivity and history of blood transfusion, transplantation, caesarean sections, deliveries, miscarriages or number of pregnancies was found. Logistic regression analysis of sociodemographic, behavioural and housing variables showed that availability of potable water at street represented a risk factor for T. gondii infection (age-adjusted OR=2.18; 95% CI: 1.05 to 4.53; p=0.03), whereas being born in Mexico was a protective factor for infection (age-adjusted OR=0.01; 95% CI: 0.001 to 0.35; p=0.008).ConclusionsIn this first study on the seroepidemiology of T. gondii infection in pregnant women in Matehuala, we conclude that the seroprevalence of T. gondii infection is low and similar to those reported in pregnant women in other Mexican cities. However, the seroprevalence found is lower than those reported in pregnant women in other countries in the Americas and Europe. Two risk factors associated with T. gondii infection were identified. Results of the present study may help for the optimal planning of preventive measures against toxoplasmosis in pregnant women.

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“…With respect to the link between infection and boar meat consumption, our results are in line with those reported in previous studies in northern Mexico. We previously found an association between T. gondii infection and boar meat consumption in several populations in Durango State, Mexico, including miners [ 25 ], elderly people [ 26 ], patients with work accidents [ 27 ], and the general urban population [ 28 ]. The results thus indicate that boar meat consumption is an important factor for T. gondii infection in northern Mexico.…”

Section: Discussionmentioning

confidence: 99%

Seroepidemiology of Toxoplasma gondii Infection in Women of Reproductive Age: A Cross-Sectional Study in a Northwestern Mexican City

et al. 2018

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BackgroundThrough a cross-sectional survey, we determined the seroprevalence and correlates of Toxoplasma gondii (T. gondii) infection in women of reproductive age in Hermosillo City, Mexico.MethodsWe studied 445 women of reproductive age in Hermosillo City in the northwestern Mexican state of Sonora. Women were enrolled in the University of Sonora. Sera of women were examined for IgG and IgM antibodies to T. gondii by commercially available enzyme immunoassays. The association of T. gondii seropositivity with the characteristics of the pregnant women was determined by bivariate and multivariate analyses.ResultsOf the 445 women (mean age: 22.18 ± 5.6 years) studied, 16 (3.6%) had IgG antibodies to T. gondii, and two (12.5%) were also positive for IgM antibodies to T. gondii. Of the 16 anti-T. gondii IgG-positive women, six (37.5%) had IgG levels higher than 150 IU/mL, four (25.0%) between 100 and 150 IU/mL, and six (37.5%) between 9 and 99 IU/mL. Multivariate analysis of socio-demographic and behavioral variables showed that T. gondii seropositivity was associated with older age (odds ratio (OR): 5.30; 95% confidence interval (CI): 1.37 - 20.50; P = 0.01) and boar meat consumption (OR: 6.86; 95% CI: 1.27 - 37.07; P = 0.02).ConclusionsWomen of reproductive age in Hermosillo City had a low seroprevalence of T. gondii infection. However, this finding indicates that most of these women were susceptible to a primary infection. Factors associated with T. gondii infection found in this study may be useful for the optimal planning of preventive measures against T. gondii infection and its sequelae.

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High Prevalence of Toxoplasma gondii Infection in Miners: A Case-Control Study in Rural Durango, Mexico

Cited by 3 publications

References 26 publications

Seroepidemiology of Toxoplasma gondii infection in people with alcohol consumption in Durango, Mexico

Seroepidemiology of Toxoplasma gondii infection in people with alcohol consumption in Durango, Mexico

Toxoplasma gondiiinfection in pregnant women: a cross-sectional study in Matehuala City, Mexico

Seroepidemiology of Toxoplasma gondii Infection in Women of Reproductive Age: A Cross-Sectional Study in a Northwestern Mexican City

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