High Prevalence of Low High-Density Lipoprotein Cholesterol Concentrations and Other Dyslipidemic Phenotypes in an Iranian Population

Sharifi, Faranak; Mousavinasab, Seyed Nouraddin; Soruri, R.; Saeini, Mohammad Reza; Dinmohammadi, Mohammadreza

doi:10.1089/met.2008.0007

Cited by 26 publications

(21 citation statements)

References 26 publications

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“…A high prevalence of low HDL-C has been reported previously in Iranian population [25, 26] and is very close to that was reported from Turkish [27]. This could not only be attributed to environmental factors but may also be due to genetic predispositions.…”

Section: Discussionsupporting

confidence: 86%

Prevalence of Metabolic Syndrome in an Adult Urban Population of the West of Iran

Sharifi

Mousavinasab

Saeini

et al. 2009

Experimental Diabetes Research

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Objectives. We determine the prevalence of the metabolic syndrome in an urban population of Zanjan, a province located to the west of Tehran. Methods. Randomly selected adults >20 years were studied using stratified sampling. Target study sample was 2941 (1396 males and 1545 females). Metabolic syndrome was diagnosed using Adult Treatment Panel-III (ATP-III) guidelines when any three of the following were present: central obesity, raised triglycerides ≥150 mg/dl, low high-density lipoprotein (HDL) cholesterol, blood pressure ≥ 130/ ≥ 85 mm Hg, and diabetes or fasting plasma glucose (FPG) ≥ 100 mg/dl. Results. Metabolic syndrome was present in 697 (23.7%) subjects (CI 95%:22%–25%, P = .001), prevalence was 23.1% in men and 24.4% in women (P : .4). The prevalence increased from 7.5% in the population younger than 30 y to 45.6% in ages more than 50 years. Low HDL was the most common metabolic abnormality in both sexes. Most of those with metabolic syndrome had three components of the syndrome (75.6%), 170 subjects (24.4%) had four and none had five components simultaneously. The prevalence of obesity (BMI ≥ 30 kg/m2), hypercholesterolemia (≥200 mg/dl) and high LDL cholesterol (≥130 mg/dl) was greater in the metabolic syndrome group than normal subjects (P = .00). Conclusions. There is a high prevalence of metabolic syndrome in this urban population of the northern west of Iran. Focus of cardiovascular prevention should be undertaken in this area.

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Section: Discussionsupporting

confidence: 86%

Prevalence of Metabolic Syndrome in an Adult Urban Population of the West of Iran

Sharifi

Mousavinasab

Saeini

et al. 2009

Experimental Diabetes Research

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“…In a survey comparing bus drivers and professional workers in Taiwan, the prevalence of high cholesterol and triglyceride levels in the drivers and professional workers was reported 34.4%, 69.4%, and 29.9%, 30.6%, respectively[25] which are similar to the results obtained from this study. The prevalence of low HDL levels is 73% and high serum triglycerides 40.6% in Iranian population [28]. In the present study increased total cholesterol (>200 mg/dl) was seen in 35.4% and high triglyceride along with low HDL in 9.9% of the population.…”

Section: Discussionsupporting

confidence: 59%

Prevalence of metabolic syndrome in bus and truck drivers in Kashan, Iran

Saberi

Moravveji

Fakharian

et al. 2011

Diabetol Metab Syndr

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BackgroundBus and truck drivers are apparently more involved in metabolic syndrome and its complications due to their working conditions. The related impacts are not only harmful for driver's health, but also may endanger others. The present research was carried out to determine the prevalence of metabolic syndrome among bus and truck drivers in Kashan, a city in Iran.MaterialsIn 2007, 429 bus and truck male drivers were enrolled to this cross sectional study to examine the metabolic syndrome using ATPIII criteria. Statistical tests including Chi-Square test, T-student test and Pearson's correlation coefficient were used to analyze the data.ResultsPrevalence of metabolic syndrome in subjects was 35.9%. Hypertension and diabetes were seen in 42.9% and 7% of the drivers respectively. Body mass index (BMI) in 41% of the drivers within the range of 25-30 was considered overweight and 23% of them were found to be obese. High triglyceride (53.4%) and low HDL-C levels (48.7%) were more common than other components of metabolic syndrome. A significant positive correlation was seen between BMI, diabetes, high blood pressure and metabolic syndrome (p < 0.001); but there was no positive correlation between metabolic syndrome and smoking (p < 0.06).ConclusionHigh prevalence of metabolic syndrome and other relevant risk factors for coronary heart diseases (CHD) were detected among the drivers. Based on these findings, it is recommended to consider training programs, establish pertinent health regulations, and focus on the metabolic syndrome complications in high risk group to improve and maintain their quality of life and to promote their public health.

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“…An association between HDL-cholesterol levels and metabolic risk factors such as coronary heart disease were shown (Vega and Grundy, 1996). Study on the components of metabolic syndrome revealed that the most frequent variations of components of metabolic syndrome was HDL-cholesterol (33.3%), which was in agreement with the findings of studies in USA (Heiss et al, 1980), Turkey (Onat et al, 1992), Italy (The Research Group ATS-RF2 of the Italian National Research Council, 1981), Canada (MacLean et al, 1999), UK (Mann et al, 1988) and Iranian population (Sharifi et al, 2008) that the most common found was high prevalence of HDL-cholesterol. According to our results, a component of metabolic syndrome such as HDL cholesterol is one of important risk factors to predict and prevent the early on set of cardiovascular disease and coronary heart disease (MacLean et al, 1999;Isomaa et al, 2001;Meigs et al, 1997;Natali et al, 2006).…”

Section: Discussionsupporting

confidence: 84%

Prevalence of Metabolic Syndrome in Baluch Women in Chabahar

Tabari¹,

Naseri²,

Majidi³

et al. 2015

International J. of Osteoporosis and Metabolic Disorders

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Epidemiological studies have shown the importance of the metabolic syndrome. With estimation of the metabolic syndrome, it may predict cardiovascular disease, sudden death and the presence of some other cardiovascular risk factors. The aim of this study was to assess the metabolic syndrome among Baluch women. Our study consisted of 120 Baluch women. Baseline data of Baluch women, prevalence of metabolic syndrome and its components and distribution of body mass index were determined. The mean Body Mass Index (BMI), waist circumference, systolic blood pressure, triglyceride, High Density Lipoprotein-Cholesterol (HDL-Chol.) and fasting blood glucose levels were significantly higher in the subjects with metabolic syndrome. The prevalence of HDL-cholesterol, high triglyceride, high fasting glucose levels, high waist circumference and high blood pressure were shown to be 33.3, 20.8, 12.5, 11.8 and 2.5%, respectively. HDL-cholesterol (33.3%) and high triglyceride levels (20.8%) were the most frequent characteristics of metabolic components. The prevalence of subject with normal weight, overweight and obese BMIs were 77.5, 15 and 7.5%, respectively. About 9.17, 4.17 and 4.17% of Baluch women had three, four and five criteria of metabolic syndrome components, respectively. This study reveals that there is a significant difference in the metabolic syndrome components in patients with and without metabolic syndrome. The prevalence of HDL-cholesterol and high triglyceride in Baluch women was highest. Definition of metabolic syndrome may help physicians to estimate, decrease and prevent coronary heart disease and cardiovascular morbidity and mortality in subjects with metabolic syndrome.

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High Prevalence of Low High-Density Lipoprotein Cholesterol Concentrations and Other Dyslipidemic Phenotypes in an Iranian Population

Abstract: The prevalence of dyslipidemia, especially low HDL cholesterol, in Iranian adults is very high. Urgent preventive programs and changes in lifestyle are needed in this area.

Cited by 26 publications

References 26 publications

Prevalence of Metabolic Syndrome in an Adult Urban Population of the West of Iran

Prevalence of Metabolic Syndrome in an Adult Urban Population of the West of Iran

Prevalence of metabolic syndrome in bus and truck drivers in Kashan, Iran

Prevalence of Metabolic Syndrome in Baluch Women in Chabahar

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