BackgroundThe prevalence of myopia among children in Chengdu is unknown. The aim of this study was to determine the prevalence of myopia in 3- to 14-year-old Chinese children in Chengdu.MethodsThis study was a school-based cross-sectional study in children aged 3–14 years. Visual acuity (VA), spherical equivalent error (SER) with noncycloplegic autorefraction, axial length (AL) and corneal radius (CR) were measured.ResultsA total of 19455 children were recruited for this study. The prevalence of myopia was 38.1%; the prevalence of low myopia was 26.6%, that of moderate myopia was 9.8%, and that of high myopia was 1.7%. The prevalence of myopia and SER increased with age from 6 years old. The prevalence of myopia was higher, and the SER indicated more severe myopia in the girls than in the boys (40.1% vs. 36.2%, χ2 = 30.67, df = 1, P < 0.001; -0.93 D±1.75 D vs. -0.84 D±1.74 D, t=3.613, df=19453, P<0.001). The girls had a higher prevalence of myopia and myopic SER than did the boys aged 9 years and older (P<0.05). Among the myopic children, the rates of uncorrected, undercorrected and fully corrected myopia were 54.8%, 17.8% and 27.4%, respectively. AL and AL/CR increased with age from 6 years old, but CR remained stable after 4 years old. The AL was longer, and the CR was flatter in the boys than in the girls aged 3 to 14 years old (P < 0.05).ConclusionThe prevalence of myopia, AL and AL/CR increased, and the SER became more myopic with age from 6 years old. The girls had a higher prevalence of myopia and myopic SER than did the boys, but the boys had a longer AL, flatter CR and higher AL/CR ratio than did the girls. The rate of uncorrected myopia was very high in the myopic children. More actions need to be taken to decrease the prevalence of myopia, especially uncorrected myopia in children.