High Prevalence of Transfusion-Transmissible Infections among Volunteer Blood Donors in Rural Area of Eastern Democratic Republic of the Congo (D.R.C)

Abstract

Background: Transfusion safety investigations in sub-Saharan Africa are sparse, often limited to local initiatives. The provision of transfusion products must comply with the rules of good transfusion practice. This study aimed to evaluate transfusion practices in a rural area in the Eastern Democratic Republic of the Congo and identifying the main Infectious Transfusion Infections. Methodology: This was a retrospective study carried out from January to December 2017 and including 961 volunteer blood donors in the haematology department of the laboratory of the Referral Health Centre of Eringeti, in the Eastern Democratic Republic of the Congo. Results: Among the 961 volunteer blood donors, 139 (14.46%) donors were found with infections transmissible by transfusion. The sex ration of 1.6 in favour of males was observed and the group age below 20 years was the most affected. The majorities of donors were single, farmers, without any level of education and reside in the village of Eringeti. Syphilis, Hepatitis B virus, Human Immunodeficiency Virus, as well as Hepatitis C Virus, were more represented respectively with 38.1%, 30.2%, 20.1% and 11.5% followed by HIV-Syphilis, syphilis-hepatitis B and syphilishepatitis B and C co-infection in the same proportion (0.7%). Ancient donors were more affected by transmissible transfusion infections with 55.4%. Conclusion: Blood safety is an essential health goal. But it is by far to be accomplished in the rural areas of the Eastern Democratic Republic of the Congo. Thus, improving the selection of donors on one hand, and the progress made in the development of more sensitive screening tools and the introduction of innovative screening measures on the other side, enhanced with a modern bank of blood with qualified staff at the Eringeti Referral Health Centre may improve the quality and safety of the blood products administered to the needy population and could thus reduce the risks ITTs in this rural area.

Level of screening for and vaccination against hepatitis B among healthcare workers in the Eastern Democratic Republic of the Congo: a public health concern

“…In Uganda and China, urban HCWs were more likely to be screened [ 7 , 20 ] possibly because of the greater availability of screening kits. The low screening and vaccination rates we observed could be due to the regular disruption of the health system in the eastern DRC due to socio-political instabilities (including war) [ 9 ]. Despite these issues, we found that HCWs who knew they were at high risk of HBV infection, understood its mode of transmission, and the benefit of vaccination were those most likely to have been screened for HBV.…”

“…In the Democratic Republic of the Congo (DRC), health and education systems have been disrupted by multiple socio-political instabilities. Although its prevalence of HBV infection is among the highest in the world [ 9 ], the overall risk of these infections to HCWs is largely unknown [ 10 ]. A survey conducted in Bukavu, a town in South Kivu DRC, revealed that HCWs had a low level of knowledge about HBV and only 3.8% of vaccinated HCWs had received the complete vaccination schedule of three vaccine doses [ 10 ].…”

Infectious Markers in Blood Donors at the Fixed Blood Collection of the Yamoussoukro Blood Transfusion Center in Côte D’ivoire

“…Despite advances in transfusion safety, transfusion-related infections remain a concern [3,4]. Indeed, according to the World Health Organization (WHO) in 2018, the prevalence of transfusion-transmitted infections in donated blood would be much lower in high-income countries than in low-and middle-income countries below [5,6]. Indeed, the seroprevalence of HIV, hepatitis B, hepatitis C, and syphilis was 0.002%, 0.02%, 0.007%, and 0.02% in high-income countries, respectively; and 0.70% 2.81% 1.00% 0.90% in low-income countries [5].…”