“…13 Later, Wang demonstrated a chemoselective condensation of alkynes, amines, and α,β-unsaturated aldehydes catalyzed by Cu(OTf) 2 (Scheme 1b ). 14 Further, the synthesis of 1,4-DHPs through a selective tandem C–C bond-forming reaction with CO 2 from enaminones was built up (Scheme 1c ). 15 Cascade cyclization synthesis strategies utilizing various C4 sources, including carbonyl compounds, alkenyl fragments, alcohols, aliphatic amines, glycines, and other sources, have been employed to construct 1,4-DHPs.…”