High-Resolution Anoscopy in the Diagnosis of Anal Cancer Precursor Lesions in Renal Graft Recipients

Silva, Ivan Tramujas da Costa e; Ferreira, Luíz Carlos de Lima; Gimenez, Felicidad Santos; Guimarães, Ricardo Alexandre Gonçalves; Fujimoto, Luciana Botinelly Mendonça; Cabral, Celso Rômulo Barbosa; Mozzer, Renzo Venturim; Atala, Larissa de Souza

doi:10.1245/s10434-007-9750-8

Cited by 28 publications

(4 citation statements)

References 26 publications

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“…A total of 214 transplant recipients underwent HRA. Studies were conducted in the United Kingdom, 12 United States, 28 and Brazil 31 . All studies were in kidney transplant recipients.…”

Section: Resultsmentioning

confidence: 99%

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Burden of anal squamous cell carcinoma, squamous intraepithelial lesions and HPV16 infection in solid organ transplant recipients: A systematic review and meta-analysis

Albuquerque

Stirrup

Nathan

et al. 2020

American Journal of Transplantation

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Anal human papillomavirus (HPV) infection, especially HPV16, is an important etiologic factor of anal precancerous lesions and anal squamous cell carcinoma (SCC). 1,2 These anal HPV complications have been shown to occur at increased rates in specific groups, such as human immunodeficiency virus (HIV)-positive patients, 3 men who have sex with men (MSM), 3 women with a previous history of genital neoplasia, 4,5 and solid organ transplant recipients

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“…A total of 214 transplant recipients underwent HRA. Studies were conducted in the United Kingdom, 12 United States, 28 and Brazil 31 . All studies were in kidney transplant recipients.…”

Section: Resultsmentioning

confidence: 99%

“…All studies were in kidney transplant recipients. Of note, 2 studies performed biopsies of abnormal areas and nonabnormal areas 12,31 and 1 from abnormal areas only 28 …”

Section: Resultsmentioning

confidence: 99%

Burden of anal squamous cell carcinoma, squamous intraepithelial lesions and HPV16 infection in solid organ transplant recipients: A systematic review and meta-analysis

Albuquerque

Stirrup

Nathan

et al. 2020

American Journal of Transplantation

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“…Although screening for anal cancer results in early detection, screening of at-risk populations has not been widely adopted. The current gold standard for anal cancer screening is high resolution anoscopy (HRA), a technique adapted from standard cervical examination protocols [4][5][6][7]. In brief, the procedure is conducted as follows: 3-5% acetic acid is applied, using a soaked gauze, into the anal canal for at least one minute.…”

Section: Introductionmentioning

confidence: 99%

A wide field-of-view scanning endoscope for whole anal canal imaging

Han¹,

Huangfu²,

Lai³

et al. 2015

Biomed. Opt. Express

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Abstract:We report a novel wide field-of-view (FOV) scanning endoscope, the AnCam, which is based on contact image sensor (CIS) technology used in commercialized business card scanners. The AnCam can capture the whole image of the anal canal within 10 seconds with a resolution of 89 μm, a maximum FOV of 100 mm × 120 mm, and a depthof-field (DOF) of 0.65 mm at 5.9 line pairs per mm (lp/mm). We demonstrate the performance of the AnCam by imaging the entire anal canal of pigs and tracking the dynamics of acetowhite testing. We believe the AnCam can potentially be a simple and convenient solution for screening of the anal canal for dysplasia and for surveillance in patients following treatment for anal cancer.

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“…While there is a long learning curve for this procedure, the sensitivity is 90.9 to 100% and specificity is 65.63 to 74.7%, positive predictive value of detecting HSIL is 47.62 to 79.8%, and negative predictive value 82.3 to 100%. 22 23 24 This technique may be performed in a clinic setting or in the operating room.…”

Section: Existing Screening/surveillance Approachesmentioning

confidence: 99%

Anal Squamous Intraepithelial Lesions and Anal Cancer Management in Low Resource Settings

Hawkins

Fang

2022

Clin Colon Rectal Surg

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A low resource setting (LRS) is defined as a health care system which does not meet the criteria defined by the World Health Organization (WHO) or other national/international organizations in the following areas: infrastructure, materials, and human resources.1 Patients encounter barriers which limit their access to care and services that are considered standard of care. While LRS is most commonly associated with developing countries, it is easy to overlook communities in developed countries which lack the financial resources to afford basic health care. This article describes the societal implications and barriers to care for both squamous intraepithelial lesions (SILs) and anal cancer in LRS, the existing screening/surveillance approaches, available treatment approaches to anal cancer, and it also discusses potential evidence-based approaches to bridge the gap for these disparities in anal cancer care.

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High-Resolution Anoscopy in the Diagnosis of Anal Cancer Precursor Lesions in Renal Graft Recipients

Cited by 28 publications

References 26 publications

Burden of anal squamous cell carcinoma, squamous intraepithelial lesions and HPV16 infection in solid organ transplant recipients: A systematic review and meta-analysis

Burden of anal squamous cell carcinoma, squamous intraepithelial lesions and HPV16 infection in solid organ transplant recipients: A systematic review and meta-analysis

A wide field-of-view scanning endoscope for whole anal canal imaging

Anal Squamous Intraepithelial Lesions and Anal Cancer Management in Low Resource Settings

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