High-resolution CT of the lungs: an optimal approach.

Mayo, John R.; Webb, W. Richard; Gould, Robert G.; Stein, M G; Bass, Isabel S; Gamsu, G; Goldberg, H I

doi:10.1148/radiology.163.2.3562834

Cited by 230 publications

(82 citation statements)

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“…The present study determined that ASIR does reduce the noise in MPR images of the lung, which is compatible with previous reports. It has previously been established that high-resolution CT (HRCT) using a thin slice thickness and a high spatial frequency algorithm should be applied to lung imaging to improve spatial resolution [16,17]. However, using a thin slice thickness and a high spatial frequency algorithm increases the visible image noise [17][18][19].…”

Section: Discussionmentioning

confidence: 99%

Image quality of multiplanar reconstruction of pulmonary CT scans using adaptive statistical iterative reconstruction

Honda¹,

Yanagawa²,

Kikuyama³

et al. 2011

BJR

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Objective: We investigated the image quality of multiplanar reconstruction (MPR) using adaptive statistical iterative reconstruction (ASIR). Methods: Inflated and fixed lungs were scanned with a garnet detector CT in highresolution mode (HR mode) or non-high-resolution (HR) mode, and MPR images were then reconstructed. Observers compared 15 MPR images of ASIR (40%) and ASIR (80%) with those of ASIR (0%), and assessed image quality using a visual five-point scale (1, definitely inferior; 5, definitely superior), with particular emphasis on normal pulmonary structures, artefacts, noise and overall image quality. Results: The mean overall image quality scores in HR mode were 3.67 with ASIR (40%) and 4.97 with ASIR (80%). Those in non-HR mode were 3.27 with ASIR (40%) and 3.90 with ASIR (80%). The mean artefact scores in HR mode were 3.13 with ASIR (40%) and 3.63 with ASIR (80%), but those in non-HR mode were 2.87 with ASIR (40%) and 2.53 with ASIR (80%). The mean scores of the other parameters were greater than 3, whereas those in HR mode were higher than those in non-HR mode. There were significant differences between ASIR (40%) and ASIR (80%) in overall image quality (p,0.01). Contrast medium in the injection syringe was scanned to analyse image quality; ASIR did not suppress the severe artefacts of contrast medium. Conclusion: In general, MPR image quality with ASIR (80%) was superior to that with ASIR (40%). However, there was an increased incidence of artefacts by ASIR when CT images were obtained in non-HR mode. Multiplanar reconstruction (MPR) of CT images plays an important role in the interpretation of the threedimensional anatomical location or extent of disease, and is an essential technique in daily clinical practice. Multidetector row CT (MDCT) is widely used, and advances in MDCT technology have facilitated better images with thinner slice thickness and extended coverage, which has allowed more MPR images to be evaluated in greater detail. Coronal MPR images produced by MDCT supply good image quality for lung assessment and show similar image quality to axial highresolution (HR) CT images [1, 2].To further enhance CT image quality, improvements in temporal resolution and/or spatial resolution are needed. MDCT equipped with more rapid gantry rotation or more detector arrays has already evolved for the improvement of temporal resolution. GE Healthcare (Milwaukee, WI) recently produced an MDCT unit containing a new detector composed of garnet, which has a faster response than the previous detector material. This apparatus can provide improved spatial resolution by acquiring more data.Reconstruction algorithms are also important for improved image quality. Although the filtered backprojection algorithm has traditionally been used for image reconstruction, new reconstruction algorithms are being developed. The iterative reconstruction algorithm has already been used for image reconstruction of positron emission tomography (PET) or single photon emission CT (SPECT), resulting in improved image quality [3][4...

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Section: Discussionmentioning

confidence: 99%

Image quality of multiplanar reconstruction of pulmonary CT scans using adaptive statistical iterative reconstruction

Honda¹,

Yanagawa²,

Kikuyama³

et al. 2011

BJR

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“…Chest CT scans were performed on a SeleCT scanner (Picker International, Haifa, Israel) in high-resolution mode according to the method of Mayo et al 16 The matrix size was 512 ϫ 512, and the scanning time was 2.1 s. Subjects were examined while supine during full deep inspiration with their arms held over their heads. Images were recorded at a window width of 1,600 Hounsfield units and at a window level of Ϫ600 Hounsfield units.…”

Section: High-resolution Ctmentioning

confidence: 99%

Factors Associated With Quality of Life in Subjects With Stable COPD

et al. 2015

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BACKGROUND: The purpose of this study was to assess the impact of bronchiectasis, anxiety and depression, and parameters of disease severity on health-related quality of life (HRQOL) in subjects with COPD. METHODS: Sixty-two subjects with stable COPD were selected for the study. The presence of bronchiectasis in all subjects with COPD was investigated by high-resolution computed tomography. Pulmonary function tests were performed. Dyspnea was assessed using the Modified Medical Research Council (MMRC) dyspnea scale. Psychological disorders were investigated using the Hospital Anxiety and Depression Scale (HADS), and the HRQOL was examined using the St George Respiratory Questionnaire (SGRQ). RESULTS: High-resolution computed tomography revealed that 44 of 62 (70.9%) subjects with COPD had bronchiectasis. There were no differences in pulmonary function tests, symptoms, activities, impact, SGRQ total scores, and HADS scores between COPD subjects with and without bronchiectasis. Pearson correlation analyses showed that there was no significant association between the presence of bronchiectasis, bronchial wall thickness, or severity of bronchial dilatation and all subscales of the SGRQ or HADS scores. Additionally, HADS scores showed significant positive association with all subscales of the SGRQ in all subjects. In linear regression analysis, a statistically significant relationship was found between the SGRQ total score and percent-of-predicted FEV 1 , percent-of-predicted diffusing capacity of the lung for carbon monoxide, MMRC score, and anxiety score, but the SGRQ total score was not associated with age, body mass index, total number of hospitalizations, P aO 2 , or depression score. CONCLUSIONS: The presence of bronchiectasis in subjects with COPD does not impact HRQOL and psychological disorders. However, disease severity, dyspnea levels, and anxiety scores predict poor HRQOL. Key words: chronic obstructive pulmonary disease (COPD); health-related quality of life (HRQOL); anxiety; depression; bronchiectasis. [Respir Care 2015;60(11):1585-1591

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“…The relationship between radiation exposure and image quality at mediastinal and pulmonary window settings has been evaluated on conventional 10-mm collimation CT images on a single model of CT scanner with mAs settings ranging from 20 to 400 mAs (19). Although this study showed a consistent increase in image quality with radiation dose, no difference in detection of mediastinal and lung abnormalities could be detected.…”

Section: New Reference Valuesmentioning

confidence: 90%

Radiation dose optimization in thoracic imaging

Tack¹

2010

Journal of the Belgian Society of Radiology

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Guidelines for reduction of CT radiation dose were introduced in 1997 and are now more than 12 years old. The process initiated by the European Regulatory authorities to reduce the excess of radiation from CT has however not produced the expected results. Reference diagnostic levels (DRL) from surveys are still twice as high as needed in most European countries and were not significantly reduced as compared to the initial European ones. Many factors may at least explain partially the lack of dose reduction. One of them is the complexity of the dose optimization process while maintaining image quality at a diagnostically acceptable level. Chest is an anatomical region where radiation dose could be substantially reduced because of high natural contrasts between structures, such as air in the lungs and fat in the mediastinum. In this article, the concept of CT radiation dose optimization and the factors that contribute to maintain global excess in radiation dose are reviewed and a brief summary of results from research in the field of chest CT radiation dose is given.

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High-resolution CT of the lungs: an optimal approach.

Cited by 230 publications

References 0 publications

Image quality of multiplanar reconstruction of pulmonary CT scans using adaptive statistical iterative reconstruction

Image quality of multiplanar reconstruction of pulmonary CT scans using adaptive statistical iterative reconstruction

Factors Associated With Quality of Life in Subjects With Stable COPD

Radiation dose optimization in thoracic imaging

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