High-Resolution Double Arterial Phase Hepatic MRI Using Adaptive 2D Centric View Ordering: Initial Clinical Experience

Abstract

High-resolution dual arterial phase 3D FSPGR MRI improves the timing of the arterial phase of liver enhancement and provides additional information for liver lesion detection.

Respiratory Motion-Resolved Compressed Sensing Reconstruction of Free-Breathing Radial Acquisition for Dynamic Liver Magnetic Resonance Imaging

“…Various studies have suggested that acquisition of multiple arterial phases can improve the detection of enhancement in liver lesions [14, 15]. Many groups perform dual arterial phase acquisition in one breath-hold to improve the conspicuity of arterial enhancement in small lesions [16]. However, the need to acquire data within a breath-hold requires a balance between temporal resolution, spatial resolution, and volumetric coverage.…”

High resolution multi-arterial phase MRI improves lesion contrast in chronic liver disease

“…Low et al found that younger patients required a shorter scan delay than older patients [9]. Kagawa et al showed a significant difference in the time of initial HCC enhancement between patients previously treated with transarterial chemoembolization and those who were treatment naïve [10].…”

“…Effective capture of the late arterial phase is essential for detection of small foci of hepatocellular carcinoma [5][6][7][8]; however, determining the precise timing of optimal contrast enhancement for detection of HCC is technically challenging because it is affected by the patient's cardiac output, choice of contrast agent, contrast injection protocol and imaging protocol [9,10]. More importantly, as with any dynamic MRI application, there is a tradeoff between spatial and temporal resolution.…”

“…Alternatively, lower spatial resolution and/or spatial coverage with multiple temporal phases and a fixed scan delay can be used to increase the probability of capturing the late arterial phase [13]. The acquisition of multiple arterial phases may increase the probability of effective late arterial phase capture, and hence increase the sensitivity of dynamic contrast-enhanced MRI for detecting hepatocellular carcinomas [9,[14][15][16].…”

Improved hepatic arterial phase MRI with 3‐second temporal resolution

“…However, this faster imaging technique with multiple arterial phases allows using a fixed scan delay method to capture the transient arterial phase by making bolus timing less critical, while keeping the acquisition simple for the operator. Low et al (12) compared single arterial phase acquisition with dual arterial phase acquisition using a fixed 20‐s delay and reported 91% optimal timing with dual phase imaging, compared with 72% with single phase imaging. Similarly in our study, using a fixed scan delay of 10 s and Spiral LAVA with sliding window reconstruction at every 3‐s temporal update rate, optimal bolus timing was achieved in 88% of patients.…”