A two-part archaeological and limnological study of the Malian Lakes Region has revealed the high research potential of the region. The exploratory reconnaissance of the Gorbi Valley, on the eastern edge of Lake Fati, identified, mapped and sampled eight new sites. The results of the survey suggest a long duration occupation of the Gorbi Valley, as well as possible connections with the populations of the Inland Niger Delta and southeastern Mauritania. The Lake Fati core represents the first lake sediment core from the western Sahel. This 5.4 m sediment core contains a continuous record of lake mud from 10.43 to 4.66 kyr BP. Analysis of the core reveals that Al and Si abundances are decoupled following a deposition of 16 cm of sand at 4.5 ka BP, with Al decreasing and Si increasing rapidly. This period of sand deposition is significantly younger than that of the transition at 5.5 ka BP recorded in marine cores from ODP site 658, taken off the Mauritanian coast, potentially extending the timeframe in which dune systems were stable and lake systems were at their highstand. While highlighting the need for more localized climate chronologies and archaeological investigations, this study may shed light on circumstances surrounding the initial colonization and further development of the Lakes Region.Résumé Une étude de la Zone Lacustre du Mali a montré la potentialité de la région en matière de recherche plus archéologique que limnologique. Une reconnaissance d'exploration effectuée dans la vallée de Gorbi, sur la côte orientale du lac de Fati, a mis au jour huit nouveaux sites. Ces sites ont été cartographiés, et des échantillons archéologiques y ont été systématiquement prélevés. Les résultats de la reconnaissance indiquent une occupation de longue durée de la vallée de Gorbi, ainsi que des Afr Archaeol Rev (2015) 32:249-266