High-resolution Manometry Findings in Patients After Sclerotherapy for Esophageal Varices

Herbella, Fernando A. M.; Colleoni, Ramiro; Bot, Luiz; Vicentine, Fernando Pompeu Piza; Patti, Marco G.

doi:10.5056/jnm15132

Cited by 5 publications

(2 citation statements)

References 19 publications

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“…Features of esophageal motility after endoscopic sclerotherapy are a defective lower sphincter and defective and hypotensive peristalsis. 10 Achalasia occurs with equal frequency in both males and females.…”

Section: Discussionmentioning

confidence: 99%

Achalasia in a Female Adolescent

Prasetyo¹,

Suryana²

2023

Cermin Dunia Kedokteran

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Achalasia is an esophageal smooth muscle motility disorder due to relaxation failure of the lower esophageal sphincter. This condition is rarely found in children; 2-5% cases occur in less than 16-year old. Case: A 16-year-old girl presented with chief complaint of regurgitation. She also complained of dysphagia, weight loss, and general weakness. Her general appearance was weak, underweight, and decreased skin turgor. Barium esophagogram demonstrated a narrowing of esophagus lumen distal to the esophagogastric junction with a “bird’s beak” appearance or rat tail sign. Esophageal achalasia was diagnosed and managed with open (laparotomy) surgical myotomy and fundoplication. Post-operative diet arrangement was carried out gradually and the patient was discharged 4 days post-surgery. Akalasia merupakan gangguan motilitas otot polos esofagus yang terjadi akibat kegagalan relaksasi lower esophageal sphincter (LES). Kondisi ini jarang ditemukan pada anak-anak; 2-5% kasus pada anak berusia di bawah 16 tahun. Kasus: Seorang remaja perempuan 16 tahun datang ke poliklinik bedah anak dengan keluhan utama regurgitasi. Anak juga mengeluh disfagia, penurunan berat badan, dan kelemahan umum. Keadaan umum anak lemah, berat badan rendah, dan penurunan turgor kulit. Esofagogram barium menunjukkan penyempitan lumen esofagus distal terhadap esophagogastric junction dengan tampakan “bird’s beak” atau tanda rat tail. Akalasia esofagus didiagnosis dan ditatalaksana dengan pembedahan laparotomi miotomi dan fundoplikasi. Pemulihan diet pasca-operasi secara perlahan dan pasien dipulangkan 4 hari pasca pembedahan

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Section: Discussionmentioning

confidence: 99%

Achalasia in a Female Adolescent

Prasetyo¹,

Suryana²

2023

Cermin Dunia Kedokteran

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“…The major GI symptoms are acid regurgitation and heartburn due to stomach content reflux into oesophagus [8]. A Japan-based study reported a higher prevalence of 24.5% among patients of gastrooesophageal reflux disease with rheumatoid arthritis compared to the general population 11.5% [9].…”

Section: Introductionmentioning

confidence: 99%

The Association between Gastrooesophageal Reflux Disease and Subsequent Rheumatoid Arthritis Occurrence

Khan¹,

Hashir²,

Mahmood³

et al. 2021

PJMHS

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Background and Aims: Rheumatologic disorders (RDs) can manifest as gastrointestinal (GI) symptoms. Patients with systemic sclerosis (SSc) frequently experience upper GI symptoms due to a lack of esophageal contractility (AC). GORD (gastro oesophageal reflux disease) is a common comorbidity in rheumatoid arthritis patients (RA).The aim of the present study was to evaluate the correlation between manifestation of rheumatoid arthritis and gastrooesophageal reflux disease. Materials and Methods: This cross-sectional study was carried out on 845 gastro-oesophageal reflux disease patients who presented to department of medicine, Qazi Hussain Ahmad Medical Complex Nowshera and Lady Reading Hospital (LRH), Peshawar for period of six months i.e from January 2020 to June 2020. Consecutive patients with were premeditated subsequently taking written informed consent. Patients with prior history of Oesophageal surgery were excluded. The demographics characteristics such as age, BMI, gender, previous history, gastrointestinal symptoms severity, analgesics, and medication usage were recorded on a pre-designed questionnaire. Inflammatory marker’s results were taken in the forms of C - reactive protein (CRP), and Erythrocyte Sedimentation Rate (ESR). Ethical approval was taken from the respective institutional review board. SPSS version 20 was used for data analysis. Results: Out of 845 GORD patients, 110 (13%) had Rheumatologic disorders (mean age 49.5± 2.6 years, 71% females). The prevalence of rheumatoid arthritis (RA), systemic lupus erythematous (SLE), and the most common systemic sclerosis (SSc) were 39 (36%), 24 (21.8%), and 47 (42.2%) respectively. Regurgitation, dysphagia, heartburn, and nausea were the most severe symptoms of gastrointestinal patients having rheumatoid disorder. The GI symptoms had no significant association with SLE, RA, and SSc severity. Upper GI symptom severity did not differentiate between RDs. Conclusion: Our study concluded that subsequent rheumatoid arthritis has a significant association with gastro-oesophageal reflux disease. Keywords: Gastro-oesophagealReflux Disease, Rheumatoid arthritis, Systemic sclerosis

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