High-resolution MR imaging of the cutis and subcutis

Krug, Barbara; Kugel, Harald; Schulze, Hans‐Joachim; Krahe, Thomas E.; Gieseke, Jürgen; Lackner, K.

doi:10.1080/02841859809172223

Cited by 6 publications

(5 citation statements)

References 17 publications

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“…Previous examinations of the skin and subcutis in BCRL have used either ultrasound (18,19) or computed tomography (CT) (20,21), while magnetic resonance imaging (MRI) has been limited to lymphedema of the leg (22,23). With regard to resolution, ultrasound (resolution 80 µm at 20 MHz) is comparable, if not better, than both CT (resolution 100–300 µm) (24) and MRI (resolution 156 µm) (25). A benefit of the current study is the use of two ultrasound machines with different frequencies, optimized for skin (20 MHz) and subcutis (7 MHz) thickness measurements.…”

Section: Discussionmentioning

confidence: 99%

Dual-Frequency Ultrasound Examination of Skin and Subcutis Thickness in Breast Cancer-Related Lymphedema

Mellor¹,

Bush²,

Stanton³

et al. 2004

Breast Journal

100

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Breast cancer-related lymphedema (BCRL) is a chronic swelling of the arm that sometimes follows breast cancer treatment. Clinically, both skin and subcutis are swollen. Edema is considered to be predominantly subcutaneous and of an even distribution. The purpose of this study was to quantify the degree and uniformity of skin and subcutis swelling around the forearms of women with BCRL. Ten women with BCRL were recruited. Both forearms were examined using 20 MHz ultrasound to visualize the skin and 7 MHz ultrasound to visualize the subcutis. Skin thickness was between the bottom of the entry-echo and the skin-subcutis boundary. Subcutis thickness was measured between the skin-subcutis boundary and the subcutis-muscle boundary. Both average skin thickness (1.97 +/- 1.00 mm) and average subcutis thickness (10.32 +/- 5.63 mm) were greater in the ipsilateral arm than in the contralateral arm (skin 1.12 +/- 0.14 mm, subcutis 5.58 +/- 2.04 mm, p < 0.01, t-test). The degree of increase in skin thickness did not vary around the arm (p > 0.05, ANOVA), while the degree of increase in subcutis thickness did vary (p < 0.05). Skin thickness correlated negatively with subcutis thickness in the contralateral arm, but correlated positively in the ipsilateral arm. The skin and subcutis are thickened in the ipsilateral arm of patients with BCRL. Skin thickness is increased uniformly around the arm and correlates strongly with the degree of swelling, while subcutis swelling varies. The measurement of skin thickness using ultrasound may form a useful clinical tool in the diagnosis of lymphedema and also aid further investigation of therapeutic techniques.

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Section: Discussionmentioning

confidence: 99%

Dual-Frequency Ultrasound Examination of Skin and Subcutis Thickness in Breast Cancer-Related Lymphedema

Mellor¹,

Bush²,

Stanton³

et al. 2004

Breast Journal

100

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“…Many studies have shown that MRI with microscopy coils can serve as a diagnostic tool for various skin lesions. Krug et al (18) demonstrated that high resolution MR images obtained by a 1.0T system using a microscopy coil with an inner diameter of 75 mm enabled visualization of the dermis, subcutaneous tissue, and muscle fascia allowing for a pattern analysis that may minimize the differential diagnosis of various skin diseases and may help to reduce the number of skin biopsies in certain indications. In a study by Gufler et al (19), high-resolution MRI with a microscopy surface coil and a high-field 1.5-T MR system proved to be a suitable method to determine the extension and depth of infiltration in regards to basal cell carcinomas of the facial region.…”

Section: Discussionmentioning

confidence: 99%

Accuracy of Preoperative MRI with Microscopy Coil in Evaluation of Primary Tumor Thickness of Malignant Melanoma of the Skin with Histopathologic Correlation

et al. 2013

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ObjectiveThe purpose of this study was to evaluate the accuracy of a preoperative MRI with microscopy coils in determining the primary tumor thickness of malignant melanoma with histopathologic correlation.Materials and MethodsEleven patients with histopathologically confirmed malignant melanoma were included in this study. MR images of the tumors were obtained with a 47-mm microscopy coil on 1.5T MR scanners and were evaluated by two radiologists, who assessed the thickness of the primary tumor on T2-weighted images (T2WI) and gadolinium-enhanced T1-weighted images with fat suppression (Gd-T1WI) and compared the results with the histopathologic findings as the reference standard. Correlations between tumor thickness on MRI and histopathologic examination were assessed using concordance correlation coefficients (CCCs). Inter- and intraobserver variabilities of tumor measurements were also assessed by intraclass correlation coefficient (ICC).ResultsAmong the 11 cases included in the study, 10 cases from the same number of patients were managed with surgical excision and one case was confirmed with punch biopsy. The primary tumor thickness measured on T2WI showed better correlation with histopathologic results, as compared with measurements taken on Gd-T1WI: the CCC of measurements on T2WI ranged from 0.64 to 0.78, indicating a substantial agreement, whereas the CCC of measurements on Gd-T1WI ranged from 0.50 to 0.61, indicating a moderate to substantial agreement. Inter- and intraobserver agreements of readers 1 and 2 were excellent for both T2WI and Gd-T1WI, with ICC ranging from 0.86 to 0.99.ConclusionMR imaging with microscopy coils may be an accurate technique in the preoperative assessment of tumor thickness in malignant melanoma, especially on T2-weighted images.

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“…The present results are the basis for analysis of hindfoot pathology (hindfoot trauma and chronic hindfoot disorders)(see Tables 1 and 2). Sectional planes and scanning parameters were standardized for a better comparison of imaging results [12,13].…”

Section: Discussionmentioning

confidence: 99%

“…The parameters for the gradient echo sequence (90 ms/21 ms/15°TR/TE/flip‐angle) were: section thickness 2 mm and field of view 150 mm. The scanning time was 7:18 min [12].…”

Section: Methodsmentioning

confidence: 99%

Surgical aspects of the hindfoot MR anatomy

Andermahr

Zähringer

Helling

et al. 2002

Foot and Ankle Surgery

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High-resolution MR imaging of the cutis and subcutis

Abstract: High-resolution MR imaging may narrow down the differential diagnosis of various skin diseases and may help to reduce the number of skin biopsies on certain indications.

Cited by 6 publications

References 17 publications

Dual-Frequency Ultrasound Examination of Skin and Subcutis Thickness in Breast Cancer-Related Lymphedema

Dual-Frequency Ultrasound Examination of Skin and Subcutis Thickness in Breast Cancer-Related Lymphedema

Accuracy of Preoperative MRI with Microscopy Coil in Evaluation of Primary Tumor Thickness of Malignant Melanoma of the Skin with Histopathologic Correlation

Surgical aspects of the hindfoot MR anatomy

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