High-Resolution MRI of Carotid Plaque With a Neurovascular Coil and Contrast-Enhanced MR Angiography: One-Stop Shopping for the Comprehensive Assessment of Carotid Atherosclerosis

Tartari, Stefano; Righi, Riccardo; Deledda, Alessandro; Capello, Katia; Soverini, Riccardo; Benea, Giorgio

doi:10.2214/ajr.10.4751

Cited by 27 publications

(15 citation statements)

References 41 publications

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“…42 . A high-resolution MR imaging and a multi-detector CT angiography have also shown very good results of ulceration detection 40,45 . The plaque ulceration might be included in the risk stratification due to its importance of generating embolic and thrombotic events.…”

Section: Surfacementioning

confidence: 97%

“…Ulceration has often been characterized as a depression of >1 mm in width and depth 36,37 ; however, its real definition is loss of endothelial lining. Noninvasive imaging evaluation is more adequately used in ACAD reserving catheter-based angiogram for endovascular interventions and it is rarely for diagnostic purposes 36,[38][39][40][41] . The sensitivity and specificity of the DU on detecting ulceration have improved over the years 36,38,39 .…”

Section: Surfacementioning

confidence: 99%

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Stratifying risk: asymptomatic carotid disease

et al. 2012

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Stroke generates significant healthcare expenses and it is also a social and economic burden. The carotid artery atherosclerotic plaque instability is responsible for a third of all embolic strokes. The degree of stenosis has been deliberately used to justify carotid artery interventions in thousands of patients worldwide. However, the annual risk of stroke in asymptomatic carotid artery disease is low. Plaque morphology and its kinetics have gained ground to explain cerebrovascular and retinal embolic events. This review provides the readers with an insightful and critical analysis of the risk stratification of asymptomatic carotid artery disease in order to assist in selecting potential candidates for a carotid intervention.

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Section: Surfacementioning

confidence: 97%

Section: Surfacementioning

confidence: 99%

Stratifying risk: asymptomatic carotid disease

et al. 2012

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“…Methemoglobin in IPH serves as an endogenous contrast agent leading to a shortened longitudinal relaxation constant T1 and hyperintensity on T1-weighted images. This hyperintense property of IPH has been noted on general-purpose T1-weighted images, including spin-echo and TOF acquisitions [16, 32]. The mask image from contrast-enhanced MRA acquisitions can also be used to detect IPH and has led to greater detection accuracy than TOF [22].…”

Section: Mri Techniquesmentioning

confidence: 99%

“…Using histologic confirmation, numerous studies have shown that MRI exhibits high contrast for internal plaque features and that combined information from multiple contrast weightings is critical for distinguishing all plaque components [11–16]. The purpose of this article is to summarize the current state of MRI of carotid atherosclerosis and to discuss the potential utility of MRI in clinical practice and research.…”

mentioning

confidence: 99%

MRI of Carotid Atherosclerosis

Kerwin

Hatsukami

Yuan

et al. 2013

American Journal of Roentgenology

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OBJECTIVE Although MRI is widely used to observe atherosclerosis impacts on the vessel lumen, MRI also depicts the size of the plaque itself, its composition, and plaque inflammation, providing information beyond simple stenosis. This article summarizes the state of evidence for a clinical role for MRI of carotid atherosclerosis. CONCLUSION MRI of carotid atherosclerosis has a proven role in pharmaceutical trials and may improve patient management once large-scale clinical trials have been completed.

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“…Biological processes, such as inflammation and neovascularization are capable of being identified by MRI. This not only could allow screening for high-risk patients, but it could also make it possible for early treatment initiation and noninvasive monitoring [33,34].…”

Section: Carotid Plaque Ulcerationmentioning

confidence: 99%

Stroke Prevention-Surgical and Interventional Approaches to Carotid Stenosis

Rajamani

2011

Neurotherapeutics

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Extracranial carotidartery stenosis is an important cause of stroke that often needs treatment with carotid revascularization. To prevent stroke recurrence, carotid endarterectomy has been well-established for many years in treating symptomatic high-and moderate-grade stenosis. Carotid stenting is an appealing, less invasive alternative to carotid endarterectomy, and several recent trials have compared the efficacy of the 2 procedures in patients with carotid stenosis. Carotid artery stenting has emerged as an important mode of therapy for high-risk patients with symtomatic highgrade stenosis. This review focuses on the current data available that will enable the clinician to decide optimal treatment strategies for patients with carotid stenosis.

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High-Resolution MRI of Carotid Plaque With a Neurovascular Coil and Contrast-Enhanced MR Angiography: One-Stop Shopping for the Comprehensive Assessment of Carotid Atherosclerosis

Abstract: In patients with carotid atherosclerosis, ongoing CE-MRA with a neurovascular coil for the simultaneous detection of unstable plaques is feasible. Our MR protocol accurately identifies the major features of vulnerable plaque.

Cited by 27 publications

References 41 publications

Stratifying risk: asymptomatic carotid disease

Stratifying risk: asymptomatic carotid disease

MRI of Carotid Atherosclerosis

Stroke Prevention-Surgical and Interventional Approaches to Carotid Stenosis

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