High-resolution X-ray diffraction to probe quantum dot asymmetry

Serafińczuk, J.; Rudno-Rudziński, W.; Gawełczyk, M.; Podemski, P.; Parzyszek, K.; Piejko, A.; Sichkovskyi, V.; Reithmaier, J.P.; Sęk, G.

doi:10.1016/j.measurement.2023.113451

Measurement

2023

DOI: 10.1016/j.measurement.2023.113451

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High-resolution X-ray diffraction to probe quantum dot asymmetry

J. Serafińczuk,

W. Rudno-Rudziński,

M. Gawełczyk

et al.

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2024

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Cited by 2 publications

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Nerve Regeneration Potential of Antioxidant-Modified Black Phosphorus Quantum Dots in Peripheral Nerve Injury

Shen,

Sun,

Liu

et al. 2024

ACS Nano

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Peripheral nerve injury is a major societal concern. Black phosphorus (BP) has inherent advantages over cell-based therapies in regenerative medicine. However, controlling spontaneous degradation and size-dependent cytotoxicity remains challenging and poses difficulties for clinical translation. In this study, we constructed zero-dimensional BP quantum dots (QDs) modified with antioxidant β-carotene and comprehensively investigated them in Schwann cells (SCs) to elucidate their potential for peripheral nerve repair. In vitro experiments demonstrated that BPQD@β-carotene has an inappreciable toxicity and good biocompatibility, favoring neural regrowth, angiogenesis, and inflammatory regulation of SCs. Furthermore, the PI3K/Akt and Ras/ERK1/2 signaling pathways were activated in SCs at the genetic, protein, and metabolite levels. The BPQD@β-carotene-embedded GelMA/PEGDA scaffold enhanced functional recovery by promoting axon remyelination and regeneration and facilitating intraneural angiogenesis in peripheral nerve injury models of rats and beagle dogs. These results contribute to advancing knowledge of BP nanomaterials in tissue regeneration and show significant potential for application in translational medicine.

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Nerve Regeneration Potential of Antioxidant-Modified Black Phosphorus Quantum Dots in Peripheral Nerve Injury

Shen,

Sun,

Liu

et al. 2024

ACS Nano

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Metal oxides on the frontlines: Antimicrobial activity in plant-derived biometallic nanoparticles

Krishnan,

Sathishkumar,

Devi

et al. 2024

Nanotechnology Reviews

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High-resolution X-ray diffraction to probe quantum dot asymmetry

Cited by 2 publications

References 29 publications

Nerve Regeneration Potential of Antioxidant-Modified Black Phosphorus Quantum Dots in Peripheral Nerve Injury

Nerve Regeneration Potential of Antioxidant-Modified Black Phosphorus Quantum Dots in Peripheral Nerve Injury

Metal oxides on the frontlines: Antimicrobial activity in plant-derived biometallic nanoparticles

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