High-Risk Factors for Suppurative Mastitis in Lactating Women

Abstract

BackgroundAcute mastitis is a common disease occurring in postpartum lactating women. This study aimed to identify the high-risk factors for suppurative mastitis (SM) in women who were breastfeeding.Material/MethodsA total of 262 non-SM patients and 63 SM patients admitted to the Department of Breast and Thyroid Surgery of Liaocheng People’s Hospital were retrospectively enrolled in this study. The high-risk factors for SM during lactation were determined by assessing admission time after acute mastitis, galactostasis, primipara or pluripara, nipple injuries, antibiotic treatment course, and diabetes.ResultsThe incidence of SM in patients with admission time greater than 72 h after occurrence of acute mastitis was significantly higher than that in patients whose admission time was less than 72 h (p<0.0001). Patients with galactostasis were more prone to develop SM compared to patients without galactostasis (p<0.0001), and the incidence of SM in primiparous patients was significantly higher than that in pluriparous patients (p=0.003). The incidence rate of SM was significantly higher in patients with diabetes than in patients without diabetes (p=0.002). Patients with nipple injuries were more prone to suffer from SM relative to the patients without nipple injuries (p<0.0001). However, there was no significant difference in the incidence of SM according to the antibiotic treatment course (p=0.134).ConclusionsSM during lactation was closely associated with admission time after the occurrence of acute mastitis, galactostasis, primipara, diabetes, and nipple injuries.

Comprehensive evaluation of the risk of lactational mastitis in Chinese women: combined logistic regression analysis with receiver operating characteristic curve

“…This finding is consistent with previous evidence [29,30] that the primiparous women were found significantly more frequent in the mastitis group than in the control group (OR = 2.233, 95%CI = 1.602-3.113). Primipara without previous experience of childbirth lacks healthcare knowledge and preventive measures for postpartum rehabilitation, breastfeeding and lactation mastitis, but also faces the adaptation process of new roles [31].…”

Mastitis as a rare inflammatory manifestation of brucellosis in human; a case report

“…Brucella mastitis in human occurs in non-lactation women, while more mastitis occurs in lactating women. (18,19). In contrast to our report, the most common form of breast infection is staphylococcal mastitis in humans, and Brucella mastitis is not primarily found in lactating women (20).…”

Antibacterial acticivity of extracts from Potentilla reptans L.

“…The stretching of alveoles from retained milk leads to reduction of its production by the alveolar epithelium. In addition to reduced milk production, galactostasis (milk retention in milk ducts and alveoles) is a prerequisite for the development of lactation mastitis (Yu et al 2018). Oxytocin plays an important role in the process of lactation and opening the milk ducts (Konar 2014) Our preliminary tests demonstrated agonistic activity of P. reptans extracts to the oxytocin and vasopressin receptors (Mincheva et al unpubl.…”