Research on the human papillomavirus (HPV) suggests a possible relation between HPV type and geography. It also demonstrates that insurance status affects HPV vaccine uptake, which currently provides protection against 9 of the high-risk HPV types known to cause HPVrelated cancers. This article reviews this literature with a focus on health justice in HPV vaccination programs. It also describes University of Illinois Health System research with members of Chicago communities to determine the prevalence of HPV, the distribution of HPV types, and strategies for better serving this population. Possible Influence of Geography on HPV Genotype Several studies have noted a high frequency of atypical high-risk HPV genotypes. Researchers in Michoacán, Mexico, noticed that there was a high frequency of "unusual virus genotypes" when they introduced a different type of testing into their methodology. 1 Specifically, it was found that HPV59 was most prevalent, along with other types (51, 45, 31, 58, 35, 39, 52, and 67) and "that HPV16 was only found in 3 coinfections and HPV18 was not found at all." Similarly, high rates of other high-risk HPV (ohrHPV) genotypes were found in patients in the Montefiore Medical Center, the Bronx, New York, which serves a racially diverse population. 2 Another study on the Midwestern population serviced by the Mayo Clinic in Rochester, Minnesota, also reported ohrHPV genotypes in its dominant diagnoses. 3