High selectivity and reversibility/reusability red emitting fluorescent probe for copper ions detection and imaging in living cells

Ni, Hanzhi; Wang, Qing-Ming; Jin, Lei; Wang, Wenling; Dai, Lihui; Zhao, Cong

doi:10.1016/j.jlumin.2018.10.066

Cited by 20 publications

(4 citation statements)

References 49 publications

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“…In 2019, Wang et al focused on the synthesis of a Congo red-conjugated Schiff base derivative and characterized it using several analytical techniques. 196 Probe- 83 was exhibited to be very selective and sensitive towards Cu( ii ) ions via colorimetric and fluorescence turn-on responses, which was based on the CHEF mechanisms in water and ethanol. Probe- 83 (Fig.…”

Section: Schiff Base-based Fluorescent Turn-on Probes For Cu(ii) Ionsmentioning

confidence: 99%

An overview of Schiff base-based fluorescent turn-on probes: a potential candidate for tracking live cell imaging of biologically active metal ions

et al. 2023

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Section: Schiff Base-based Fluorescent Turn-on Probes For Cu(ii) Ionsmentioning

confidence: 99%

An overview of Schiff base-based fluorescent turn-on probes: a potential candidate for tracking live cell imaging of biologically active metal ions

et al. 2023

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“…It has also been explored as a fluorescent chemosensor for detecting various analytes, including metal ions and biological molecules. Ni et al reported probe−13, a Schiff base Cu 2+ tracker synthesized via a one-step process by refluxing 1-hydroxynaphthalene-2-carbaldehyde and Congo red in ethanol [77]. The methodology offers a detailed account of the synthesis process and the characterization techniques.…”

Section: Schiff Bases As Chemosensors For Cu 2+mentioning

confidence: 99%

Strategies for Improving Selectivity and Sensitivity of Schiff Base Fluorescent Chemosensors for Toxic and Heavy Metals

Musikavanhu,

Liang,

Xue

et al. 2023

Molecules

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Toxic cations, including heavy metals, pose significant environmental and health risks, necessitating the development of reliable detection methods. This review investigates the techniques and approaches used to strengthen the sensitivity and selectivity of Schiff base fluorescent chemosensors designed specifically to detect toxic and heavy metal cations. The paper explores a range of strategies, including functional group variations, structural modifications, and the integration of nanomaterials or auxiliary receptors, to amplify the efficiency of these chemosensors. By improving selectivity towards targeted cations and achieving heightened sensitivity and detection limits, consequently, these strategies contribute to the advancement of accurate and efficient detection methods while increasing the range of end-use applications. The findings discussed in this review offer valuable insights into the potential of leveraging Schiff base fluorescent chemosensors for the accurate and reliable detection and monitoring of heavy metal cations in various fields, including environmental monitoring, biomedical research, and industrial safety.

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“…Compared to other methods, fluorescent probes can penetrate deep into the tissue, reducing the interference of the autofluorescence of samples, and thus realizing the detection of biological samples. Fluorescent probes Molecules 2023, 28, 6921 2 of 13 have been synthesized primarily by relying on a diverse array of sensing mechanisms, including excited-state intramolecular proton transfer (ESIPT) [14][15][16], chelation-enhanced fluorescence (CHEF) [17][18][19], photoinduced electron transfer (PET) [20][21][22], intramolecular charge transfer (ICT) [23,24], and aggregation-induced enhanced emission (AIEE) [25,26]. ESIPT based fluorescent probes exhibit unique excited-state photophysical properties of high fluorescence quantum yield and large Stokes shift.…”

Section: Introductionmentioning

confidence: 99%

Theoretical Investigation on the “ON-OFF” Mechanism of a Fluorescent Probe for Thiophenols: Photoinduced Electron Transfer and Intramolecular Charge Transfer

Wang,

Zhang,

et al. 2023

Molecules

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In this study, the sensing mechanism of (2E,4E)-5-(4-(dimethylamino)phenyl)-1-(2-(2,4dinitrophenoxy)phenyl)penta-2,4-dien-1-one (DAPH-DNP) towards thiophenols was investigated by density functional theory (DFT) and time-dependent DFT (TD-DFT). The DNP group plays an important role in charge transfer excitation. Due to the typical donor-excited photo-induced electron transfer (d-PET) process, DAPH-DNP has fluorescence quenching behavior. After the thiolysis reaction between DAPH-DNP and thiophenol, the hydroxyl group is released, and DAPH is generated with the reaction showing strong fluorescence. The fluorescence enhancement of DAPH is not caused by an excited-state intramolecular proton transfer (ESIPT) process. The potential energy curves (PECs) show that DAPH-keto is less stable than DAPH-enol. The frontier molecular orbitals (FMOs) of DAPH show that the excitation process is accompanied by intramolecular charger transfer (ICT), and the corresponding character of DAPH was further confirmed by hole-electron and interfragment charge transfer (IFCT) analysis methods. Above all, the sensing mechanism of the turn-on type probe DAPH-DNP towards thiophenol is based on the PET mechanism.

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High selectivity and reversibility/reusability red emitting fluorescent probe for copper ions detection and imaging in living cells

Cited by 20 publications

References 49 publications

An overview of Schiff base-based fluorescent turn-on probes: a potential candidate for tracking live cell imaging of biologically active metal ions

An overview of Schiff base-based fluorescent turn-on probes: a potential candidate for tracking live cell imaging of biologically active metal ions

Strategies for Improving Selectivity and Sensitivity of Schiff Base Fluorescent Chemosensors for Toxic and Heavy Metals

Theoretical Investigation on the “ON-OFF” Mechanism of a Fluorescent Probe for Thiophenols: Photoinduced Electron Transfer and Intramolecular Charge Transfer

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