High-Sensitivity C-Reactive Protein in Systemic Lupus Erythematosus Patients without Cardiac Involvement: Relation to Disease Activity and Intima-Media Thickness

Zohri, Mona H. EL

doi:10.18535/jmscr/v5i3.78

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2020

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“…Though anticardiolipin is not a marker of disease activity, ds DNA and CRP can be used as a marker of disease activity in low resource settings. 12,13 This case illustrated the difficulty in differentiating between peripartum cardiomyopathy and lupus myocarditis. Though cardiac MRI and endomyocardial biopsy are helpful they are rarely available in low resources setting.…”

Section: Discussionmentioning

confidence: 95%

Peripartum Cardiomyopathy and Systemic Lupus Erythematosus Carditis, a diagnostic dilemma

Poudel¹,

P²,

Lamsal³

et al. 2020

Nepalese Heart J.

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A young woman at 8 months postpartum presented with dyspnoea, orthopnoea and swelling of lower limbs in which physical examination, chest radiography and echocardiogram were suggestive of acute congestive heart failure with left ventricle dilatation and dysfunction. A suspicion of peripartum cardiomyopathy was made and treated with conventional drug therapy but the patient continued to develop multiple episodes of heart failure. Over time she developed fever and polyarthritis following which autoantibodies, complement level and 24-hour urinary protein were done which helped us to make the diagnosis of Systemic Lupus Erythematosus (SLE) nephritis. The patient was started on high dose corticosteroids. However, after a week, patient developed cardiogenic shock following which intravenous pulse Cyclophosphamide was started and the patient improved clinically and biochemically.

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Section: Discussionmentioning

confidence: 95%

Peripartum Cardiomyopathy and Systemic Lupus Erythematosus Carditis, a diagnostic dilemma

Poudel¹,

P²,

Lamsal³

et al. 2020

Nepalese Heart J.

View full text Add to dashboard Cite

show abstract

High-Sensitivity C-Reactive Protein in Systemic Lupus Erythematosus Patients without Cardiac Involvement: Relation to Disease Activity and Intima-Media Thickness

Abstract: Objectives: measuring hs-CRP in SLE patients without clinical cardiac involvement and finds its relation to disease activity and carotid intima media thickness (CIMT

Cited by 1 publication

References 24 publications

Peripartum Cardiomyopathy and Systemic Lupus Erythematosus Carditis, a diagnostic dilemma

Peripartum Cardiomyopathy and Systemic Lupus Erythematosus Carditis, a diagnostic dilemma

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