High Sensitivity pH Sensor Based on Porous Silicon (PSi) Extended Gate Field-Effect Transistor

Al-Hardan, Naif H.; Hamid, Muhammad Azmi Abdul; Ahmed, Naser M.; Jalar, Azman; Shamsudin, Roslinda; Othman, Norinsan Kamil; Keng, Lim Kar; Chiu, Wee Siong; Alrawi, Hamzah Naser

doi:10.3390/s16060839

Cited by 76 publications

(49 citation statements)

References 48 publications

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“…The sensor considers stability to be in the pH range of 2-12 was considered highly stable for the sensors based on PSi. The hysteresis values of the proposed PSi sensor were approximately 10.5 and 8.2 mV in the high and low pH loop, respectively [47]. Some of the drawbacks of these PSi based sensors include less specificity, high cost and complicated operation.…”

Section: Tg Biosensors Based On Porous Siliconmentioning

confidence: 96%

Recent trends and perspectives in enzyme based biosensor development for the screening of triglycerides: a comprehensive review

Hooda

Gahlaut

Gothwal

2018

Artificial Cells, Nanomedicine, and Biotechnology

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Clinical manifestations of the elevated plasma triacylglycerol (TG) include a greater prevalence of atherosclerotic heart disease, acute pancreatitis, diabetes mellitus, hypertension, and ischemic vascular disease. Hence, these significant health troubles have attracted scientific attention for the precise detection of TG in biological samples. Numerous techniques have been employed to quantify TG over many decades, but biosensors hold the leading position owing to their superior traits such as highly specific recognition for target molecules, accuracy, minituarization, small sample requirement and rapid response. Enzyme-based electrochemical biosensors represent an instantaneous resolution for the foremost bottlenecks constraining laboratory prototypes to reach real time bedside applications. We highlight the choice of transducers and constructive strategies to design high-performance biosensor for the quantification of triglycerides in sera and early diagnosis of health problems related to it. In the present review, a small effort has been made to emphasize the significant role of enzymes, nanostructured metal oxides, graphene, conducting polypyrrole, nanoparticles, porous silicon, EISCAP and ENFET in enabling TG biosensors more proficient and taking a revolutionary step forward.

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Section: Tg Biosensors Based On Porous Siliconmentioning

confidence: 96%

Recent trends and perspectives in enzyme based biosensor development for the screening of triglycerides: a comprehensive review

Hooda

Gahlaut

Gothwal

2018

Artificial Cells, Nanomedicine, and Biotechnology

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“…, pHPZC corresponds to the pH value for which the surface charge is null, k is the Boltzmann's constant, T is the temperature and β is the buffer capacity, a parameter that characterizes the ability of the sensitive surface to buffer pH changes (β is an inherent property of the sensing material). According to the site-binding model, the number of binding sites on the sensing membrane can change the potential of the electrolytic interface, as well as the potential of the sensing membrane, that is expressed by [74]:…”

Section: Ph Sensorsmentioning

confidence: 99%

EGFET Based Sensors for Bioanalytical Applications: A Review

Pullano¹,

Critello²,

Mahbub³

et al. 2018

Preprint

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Since 1970s, a great deal of attention has been paid to the development of semiconductor–based biosensors because of the numerous advantages they offer, including high sensitivity, faster response time, miniaturization, and low–cost manufacturing for quick biospecific analysis with reusable features. Commercial biosensors have become highly desirable in the fields of medicine, food, environmental monitoring as well as military applications (e.g., Hoffmann–La Roche, Abbott Point of Care, Orion High technologies, etc.), whereas increasing concerns on the food safety and health issues have resulted in the introduction of novel legislative standards for these sensors. Numerous devices have been developed for monitoring of biological–processes such as nucleic–acid hybridization, protein–protein interaction, antigen–antibody bonds and substrate–enzyme reactions, just to name a few. Since 1980s scientific interest moved to the development of semiconductor–based devices which also include integrated front–end electronics, such as the extended–gate–field–effect–transistor biosensor which is one of the first miniaturized chemical sensors. This work is intended to be a review of the state of the art focused on the development of biosensors based extended–gate–field–effect–transistor within the field of bioanalytical applications, which will highlight the most recent research works reported in the literature. Moreover, a comparison among the diverse EGFET devices will be presented giving particular attention to the materials and technologies.

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“…Macroporous silicon (MPS) has attracted the attention of several groups, owing to the well-known advantages of its large surface area and biocompatibility [ 1 ], as well as its showing promising behavior in several advanced applications, such as gas sensing [ 2 , 3 ], pH sensors [ 4 ], biochips [ 5 ], CMOS devices [ 6 ], drug delivery devices [ 1 ], biosensors [ 7 , 8 ], and in fuel cell devices [ 9 ] and waveguides [ 10 ]. Furthermore, it can be simply integrated with silicon technology processes [ 11 ].…”

Section: Introductionmentioning

confidence: 99%

Electrochemical Hydrogen Peroxide Sensor Based on Macroporous Silicon

Al-Hardan

Hamid²,

Shamsudin³

et al. 2018

Sensors

Self Cite

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Macroporous silicon was prepared through an anodization process; the prepared samples showed an average pore size ranging from 4 to 6 microns, and the depth of the pores in the silicon wafer was approximately 80 microns. The prepared samples were tested for hydrogen peroxide (H2O2) concentrations, which can be used for industrial and environmental sensing applications. The selected H2O2 concentration covered a wide range from 10 to 5000 μM. The tested samples showed a linear response through the tested H2O2 concentrations with a sensitivity of 0.55 μA μM–1∙cm–2 and lower detection limits of 4.35 μM at an operating voltage of 5 V. Furthermore, the electrode exhibited a rapid response with a response time of ca. two seconds. Furthermore, the prepared sensor showed a reasonable stability over a one-month time period.

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High Sensitivity pH Sensor Based on Porous Silicon (PSi) Extended Gate Field-Effect Transistor

Cited by 76 publications

References 48 publications

Recent trends and perspectives in enzyme based biosensor development for the screening of triglycerides: a comprehensive review

Recent trends and perspectives in enzyme based biosensor development for the screening of triglycerides: a comprehensive review

EGFET Based Sensors for Bioanalytical Applications: A Review

Electrochemical Hydrogen Peroxide Sensor Based on Macroporous Silicon

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