High Sensitivity Terahertz Biosensor Based on Mode Coupling of a Graphene/Bragg Reflector Hybrid Structure

Zheng, Qiwen; Yuan, Hongxia; Wang, Shenping; Yin, Keqiang; Dai, Xiaoyu; Zou, Xiao; Jiang, Leyong

doi:10.3390/bios11100377

Cited by 6 publications

(2 citation statements)

References 45 publications

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“…The above limitations are significantly improved with the introduction of both BDS and defect layers and with appropriate parameter settings. Their introduction leads to the excitation of both modes, which is corroborated by the enhancement of the local field at the location of the BDS and the defect layer [ 37 ]. At this point, the downward reflected peak of the OTS and the downward reflected peak of the defect mode are superimposed to produce a sharp upward reflected peak, which is typical of the Fano resonance phenomenon.…”

Section: Resultsmentioning

confidence: 99%

Terahertz Biosensor Based on Mode Coupling between Defect Mode and Optical Tamm State with Dirac Semimetal

Bao

Ren

et al. 2022

Biosensors

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Bulk Dirac semimetal (BDS) has emerged as a “3D graphene” material for the development of optical devices in the past few years. In this study, a BDS-based tunable highly sensitive terahertz (THz) biosensor is proposed by using a Dirac semimetal/Bragg reflector multilayer structure. The high sensitivity of the biosensor originates from the sharp Fano resonance peak caused by coupling the Optical Tamm State (OTS) mode and defect mode. Besides, the sensitivity of the proposed structure is sensitive to the Fermi energy of Dirac semimetal and the refractive index of the sensing medium. The maximum sensitivity of 1022°/RIU is obtained by selecting structural and material parameter appropriately, which has certain competitiveness compared to conventional surface plasmon resonance (SPR) sensors. From the standpoint of the fabrication facility and integration, we judged that the BDS-based layered structure has the potential application in biosensor field.

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Section: Resultsmentioning

confidence: 99%

Terahertz Biosensor Based on Mode Coupling between Defect Mode and Optical Tamm State with Dirac Semimetal

Bao

Ren

et al. 2022

Biosensors

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“…Due to its prominent characteristics, TPP has wide applications in sensing [21], lasing [22,23], perfect absorber [24], solar cell [25], optical filtering [26], and nonlinear optics [27]. In particular, TPP sensing has been demonstrated for detection of temperature [28], pressure [29], surface deformation [30], refractive index (R.I.) [31], organic vapor [32], greenhouse gases [33], liquids [34], fat concentration in milk [35], blood components [36], and theoretically predicted to be suitable for biosensing [37]. On the other hand, porous silicon (PSi) is an outstanding material for biosensing due to its high surface area of more than 100 m 2 per 1 cm 2 of planar surface area of etched silicon [38,39], versatile biofunctionalization chemistry, and CMOS (Complementary Metal Oxide Semiconductor) compatible fabrication process [40].…”

Section: Introductionmentioning

confidence: 99%

Tamm Plasmon Polariton Biosensors Based on Porous Silicon: Design, Validation and Analysis

Rong,

Sawan

2023

Biosensors

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Tamm Plasmon Polariton (TPP) is a nanophotonic phenomenon that has attracted much attention due to its spatial strong field confinement, ease of mode excitation, and polarization independence. TPP has applications in sensing, storage, lasing, perfect absorber, solar cell, nonlinear optics, and many others. In this work, we demonstrate a biosensing platform based on TPP resonant mode. Both theoretical analyses based on the transfer matrix method and experimental validation through nonspecific detection of liquids of different refractive indices and specific detection of SARS-CoV-2 nucleocapsid protein (N-protein) are presented. Results show that the TPP biosensor has high sensitivity and good specificity. For N-protein detection, the sensitivity can be up to 1.5 nm/(µg/mL), and the limit of detection can reach down to 7 ng/mL with a spectrometer of 0.01 nm resolution in wavelength shift. Both nonspecific detection of R.I. liquids and specific detection of N-protein have been simulated and compared with experimental results to demonstrate consistency. This work paves the way for design, optimization, fabrication, characterization, and performance analysis of TPP based biosensors.

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Recent progress in Fano-resonant terahertz metasurface and its application

Chen,

Gao,

Sun

et al. 2024

Discov Appl Sci

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The unique electromagnetic response characteristics of metasurfaces and their intrinsic physical mechanisms have attracted a lot of attention. With the help of metasurfaces, the amplitude, phase, polarization, and other information of light waves can be effectively modulated. Fano resonance with asymmetric and sharp line shape is sensitive to refractive index changes in the environment, it can be realized through the structure design of the metasurface. Terahertz wave is located between microwave and infrared waves and can be used in the fields of high-sensitivity detection, high-precision imaging, and wireless communication. Terahertz metasurface with sharp Fano resonance is promising in realizing highly sensitive detection of biological macromolecules, such as glioma cells and other substances, which has attracted more and more attention. Here we review the progress of passive or active terahertz metasurfaces with Fano resonances due to various operation mechanisms and their applications in sensitive sensing.

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High Sensitivity Terahertz Biosensor Based on Mode Coupling of a Graphene/Bragg Reflector Hybrid Structure

Cited by 6 publications

References 45 publications

Terahertz Biosensor Based on Mode Coupling between Defect Mode and Optical Tamm State with Dirac Semimetal

Terahertz Biosensor Based on Mode Coupling between Defect Mode and Optical Tamm State with Dirac Semimetal

Tamm Plasmon Polariton Biosensors Based on Porous Silicon: Design, Validation and Analysis

Recent progress in Fano-resonant terahertz metasurface and its application

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