High Specific and Rapid Detection of Cannabidiol by Gold Nanoparticle-Based Paper Sensor
Yufeng Sun,
Dong Zhu,
Ran Tao
et al.
Abstract:In order to facilitate monitoring of cannabidiol (CBD), we devised a gold immunochromatographic sensor based on a specific monoclonal antibody (mAb). To prepare the antigen, a novel hapten with CBD moiety and a linear carbon chain was employed. By utilizing hybridoma technology, a specific mAb was screened and identified that exhibited a 50% maximal inhibitory concentration against CBD ranging from 28.97 to 443.97 ng/mL. Extensive optimization led to the establishment of visual limits of detection for CBD, ach… Show more
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