High-speed electron microscopy

Bostanjoglo, O.

doi:10.1016/s1076-5670(02)80024-6

Cited by 43 publications

(16 citation statements)

References 68 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Such pulses, which were used to study laser-induced melting in metals, pack within them the large number of electrons (∼10 8 ) that are detrimental to achieving ultrashort pulse imaging. Moreover, because the time window for imaging in those experiments is nanoseconds, the uncertainty in spatial resolution due to noise statistics is on the order of micrometers, as pointed out by Bostanjoglo (71). In fact our attempt to use amplified femtosecond light pulses with much higher peak power density (on the order of 10 12 W/cm 2 ) resulted in electron bunches that were impervious to focusing by the microscope optics, and no doubt much broader pulses due to electron-electron repulsion.…”

Section: Ultrafast Electron Microscopymentioning

confidence: 99%

4d Ultrafast Electron Diffraction, Crystallography, and Microscopy

Zewail

2006

Annu. Rev. Phys. Chem.

500

341

View full text Add to dashboard Cite

■ Abstract In this review, we highlight the progress made in the development of 4D ultrafast electron diffraction (UED), crystallography (UEC), and microscopy (UEM) with a focus on concepts, methodologies, and prototypical applications. The joint atomic-scale resolutions in space and time, and sensitivity reached, make it possible to determine complex transient structures and assemblies in different phases. These applications include studies of isolated chemical reactions (molecular beams), interfaces, surfaces and nanocrystals, self-assembly, and 2D crystalline fatty-acid bilayers. In 4D UEM, we are now able, using timed, single-electron packets, to image nano-to-micro scale structures of materials and biological cells. Future applications of these methods are foreseen across areas of physics, chemistry, and biology.

show abstract

Section: Ultrafast Electron Microscopymentioning

confidence: 99%

4d Ultrafast Electron Diffraction, Crystallography, and Microscopy

Zewail

2006

Annu. Rev. Phys. Chem.

500

341

View full text Add to dashboard Cite

show abstract

“…Methods to acquire electron microscopic images with much shorter exposure times than video rates have progressed through several stages since the 1960's [1][2][3], notably from the group of Prof. O. Bostanjoglo at TU Berlin [4]. The methods generally fall into two approaches, stroboscopic and single shot.…”

Section: Introductionmentioning

confidence: 99%

“…In contrast, the single shot imaging method described here, while also following the developments of Bostanjoglo [4,[18][19][20][21][22][23], acquires an electron micrograph with a single pulse of electrons [24]. The requirement of image formation with a single pulse of electrons places stringent conditions on the electron emission and is controlled, as is usual in electron microscopy, by the brightness of the source [25].…”

Section: Introductionmentioning

confidence: 99%

Quantifying transient states in materials with the dynamic transmission electron microscope

Campbell

LaGrange

Kim

et al. 2010

Journal of Electron Microscopy

View full text Add to dashboard Cite

(250 words)The Dynamic Transmission Electron Microscope (DTEM) offers a means of capturing rapid evolution in a specimen through in-situ microscopy experiments by allowing 15 ns electron micrograph exposure times. The rapid exposure time is enabled by creating a burst of electrons at the emitter by ultraviolet pulsed laser illumination. This burst arrives a specified time after a second laser initiates the specimen reaction. The timing of the two Q-switched lasers is controlled by highspeed pulse generators with a timing error much less than the pulse duration. Both diffraction and imaging experiments can be performed, just as in a conventional TEM. The brightness of the emitter and the total current control the spatial and temporal resolutions. We have demonstrated 7 nm spatial resolution in single 15 ns pulsed images. These single-pulse imaging experiments have been used to study martensitic transformations, nucleation and crystallization of an amorphous metal, and rapid chemical reactions. Measurements have been performed on these systems that are possible by no other experimental approaches currently available.2

show abstract

“…Moreover, as noted in [28], the uncertainty in the spatial resolution in these experiments due to statistical interferences was of the order of micrometers, because the temporal window for imaging was on a nanosecond scale. It was found, that the use of amplified femtosecond light pulses, with much higher intensity of about 12 2 10 W cm , led, at first, to the formation of an electron beam that was insensitive to the focusing system of the microscope, and, secondly, to a significant lengthening of the pulse, which was due to electron-electron Coulomb repulsion.…”

Section: Ultrafast Electron Microscopy For Chemistry Biology and Matmentioning

confidence: 74%

Ultrafast Electron Microscopy for Chemistry, Biology and Material Science

Aseyev¹,

Weber²,

Ischenko³

2013

JASMI

View full text Add to dashboard Cite

For the past thirty years, intense efforts have been made to record atomic scale movies that reveal the movement of atoms in molecules, the fast dynamical processes in biological tissues and cells, and the changes in the structure of a solid confined to nano-scale volumes. A combination of sub-nanometer spatial resolution with picosecond or even femtosecond temporal resolution is required for such atomic movies. Additional important information can be obtained when the energy of the electron beam transmitted through the sample is measured. The four dimensional (4D) spatially and temporally resolved ultrafast electron microscopy method is made possible by the extremely high detection efficiency that is reached in 4D electron microscopy. Using ultra-short electron bunches for the visualization of biological tissue can also improve the spatial resolution compared to conventional electron microscopes, thereby enabling the study of complex biological samples of relevance to the life sciences. Of particular interest to a broad audience is the possibility to create a video, and in the future, a real atomic movie, using 4D electron tomography. IntroductionSince the 1980s, intense efforts have been made to record an atomic movie showing the movements of atoms within molecules, the fast dynamical processes in biological tissues and cells, and the changes in the structure of a solid in a nano-scale volume [1][2][3]. Such an atomic movie requires a combination of sub-nanometer spatial resolution with picosecond or even femtosecond temporal resolution. The aim of any microscopy is to study the structure, composition, and a variety of physical and chemical characteristics of samples (usually solids) on a very small length scale, with linear dimensions of irregularities that are on the order of micrometers or nanometers. While in most microscopies, photon beams (in optical microscopy) or corpusclar beams (for example in electron microscopy) are used as the probes, tunneling microscopies use a very sharp tip that is scanned across surfaces. Electron microscopy and optical microscopy use light and a focused electron beam for imaging, respectively. Beyond those, other microscopic methods may use ions, protons, positrons, or neutrons, or acoustic or microwave radiation in addition to other, less common, methods [3][4][5][6]. In each of them, the specificity of the interaction of a beam of the particles (or photons) and the molecules or atoms of a sample yield unique and rather useful information about the structure, composition and microscopic inhomogeneities of the sample, and the nature of their intermolecular interactions [3,4,7]. For example, the slow neutrons in neutron microscopy and spectroscopy barely interact with the electrons, but interact strongly with the nuclei of the atoms.There are two main approaches to achieve imaging in classical microscopy: 1) In transmission mode, a large area of the sample is illuminated by a beam of light or particles. Specifically designed lenses project the transmitted beam onto a...

show abstract

High-speed electron microscopy

Cited by 43 publications

References 68 publications

4d Ultrafast Electron Diffraction, Crystallography, and Microscopy

4d Ultrafast Electron Diffraction, Crystallography, and Microscopy

Quantifying transient states in materials with the dynamic transmission electron microscope

Ultrafast Electron Microscopy for Chemistry, Biology and Material Science

Contact Info

Product

Resources

About