Thermalization process of nuclear matter in central fireball region of heavy-ion collisions is investigated by employing an extension model of Boltzmann-Uehling-Uhlenbeck, namely the Van der Waals Boltzmann-Uehling-Uhlenbeck (VdWBUU) model. Temperature (T ) is extracted by the quantum Fermion fluctuation approach and other thermodynamic quantities, such as density (ρ), entropy density (s), shear viscosity (η), isospin diffusivity (DI ) and heat conductivity (κ), are also deduced. The liquid-like and gas-like phase signs are discussed through the behavior of shear viscosity during heavy-ion collisions process with the VdWBUU model.