High throughput continuous synthesis of size-controlled nanoFe3O4 in segmented flow

Microfluidic synthesis of nanomaterials for biomedical applications

“…The advantages of segmented-flow synthesis include homogenous synthesis conditions, compatibility to extreme synthesis conditions, and resistance to reactor fouling, 67,68 enabling the production of high-quality nanoparticles from a wide range of material types. 69–72 Several in-depth review papers are available on segmented-flow microfluidic synthesis. 73–75…”

Continuous Preparation of Fe3O4 Nanoparticles with Narrow Size Distribution by Partial Oxidation Coprecipitation of Fe2+ Ions in Microchannels

“…Utilizing this gas–liquid segmented flow approach, we have achieved the continuous synthesis of Fe 3 O 4 nanoparticles through the coprecipitation of Fe 2+ and Fe 3+ at a temperature of 50 °C. Moreover, the average particle size can be precisely controlled to be approximately 6 nm 4 Fe 2 + + O 2 + 4 H + = 4 Fe 3 + + 2 H 2 O Fe 2 + + 2 Fe 3 + + 8 OH − = Fe 3 O 4 ↓ + 4 H 2 O …”